Veru Announces Presentation of Phase 3 Study of Sabizabulin for the Treatment of Hospitalized COVID-19 Patients at High Risk for Acute Respiratory Distress Syndrome at the 11th International Conference on Emerging Infectious Diseases (ICEID) on August 7-10, 2022 ir.verupharma.com/news-ev…
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Fecal microbiota transplantation in the treatment of irritable bowel syndrome: a single-center prospective study in Japan (Jul 2022, n=17) "about 60% of Japanese patients with IBS showed improvement in both the IBS-SI and BSFS, without severe side effects" bmcgastroenterol.biomedce…
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VERU | Veru Announces Presentation of Phase 3 Study of Sabizabulin for the Treatment of Hospitalized COVID-19 Patients at High Risk for Acute Respiratory Distress Syndrome at the 11th International Conference on Emerging Infectious Diseases (ICEID) on August 7-10, 2022 stocktitan.net/news/VERU/…
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Veru Announces Presentation of Phase 3 Study of Sabizabulin for the Treatment of Hospitalized COVID-19 Patients at High Risk for Acute Respiratory Distress Syndrome at the 11th International Conference on Emerging Infectious Diseases (ICEID) on August 7-10, 2022 ca.finance.yahoo.com/news…
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πŸ“°︎ r/swingtrading
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πŸ‘€︎ u/AsAboveSoBelow322
πŸ“…︎ Aug 09
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Veru Announces Presentation of Phase 3 Study of Sabizabulin for the Treatment of Hospitalized COVID-19 Patients at High Risk for Acute Respiratory Distress Syndrome at the 11th International Conference on Emerging Infectious Diseases (ICEID) on August 7-10, 2022 ca.finance.yahoo.com/news…
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πŸ“°︎ r/BioTechCompanies
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πŸ‘€︎ u/waxingeloquence
πŸ“…︎ Aug 09
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Fecal microbiota transplantation in the treatment of irritable bowel syndrome: a single-center prospective study in Japan (Jul 2022, n=17) "about 60% of Japanese patients with IBS showed improvement in both the IBS-SI and BSFS, without severe side effects" bmcgastroenterol.biomedce…
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πŸ“°︎ r/ibs
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πŸ‘€︎ u/MaximilianKohler
πŸ“…︎ Jul 18
🚨︎ report
Fecal microbiota transplantation in the treatment of irritable bowel syndrome: a single-center prospective study in Japan (Jul 2022, n=17) "about 60% of Japanese patients with IBS showed improvement in both the IBS-SI and BSFS, without severe side effects" bmcgastroenterol.biomedce…
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πŸ‘€︎ u/MaximilianKohler
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A new study shows that a potential treatment for Alzheimer’s disease may also improve cognitive function in people with Down syndrome. news.cuanschutz.edu/news-…
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πŸ“…︎ Mar 29
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[Article] Treatments of chronic fatigue syndrome and its debilitating comorbidities: a 12-year population-based study

J Transl Med

. 2022 Jun 11;20(1):268. doi: 10.1186/s12967-022-03461-0.

Treatments of chronic fatigue syndrome and its debilitating comorbidities: a 12-year population-based study

Kam-Hang Leong # 1 2,Β Hei-Tung Yip # 3,Β Chien-Feng Kuo # 1 4 5,Β Shin-Yi Tsai 6 7 8 9 10Affiliations expand

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A new study shows that a potential treatment for Alzheimer’s disease sargramostim may also improve cognitive function in people with Down syndrome. news.cuanschutz.edu/news-…
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Chinese study: RemeGen's Telitacicept Demonstrates Positive Results in Phase II Trial in Treatment of Primary SjΓΆgren's Syndrome prnewswire.com/news-relea…
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πŸ‘€︎ u/GETitOFFmeNOW
πŸ“…︎ Jan 25
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Your smartphone is making you hallucinate. It’s called β€œphantom vibration syndrome” β€” yes, it’s a real psychological phenomenon β€” and studies in the past few years have found, when surveying college undergraduates, that the majority experience a β€œphantom vibration” once every two weeks. nypost.com/2016/01/05/you…
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πŸ“°︎ r/psychology
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πŸ‘€︎ u/xxarlie87
πŸ“…︎ Jun 29
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A new study shows that a potential treatment for Alzheimer’s disease may also improve cognitive function in people with Down syndrome. news.cuanschutz.edu/news-…
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πŸ“°︎ r/downsyndrome
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πŸ“…︎ Mar 30
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Are people with Down Syndrome aware of the special treatment they get?

For example, if they're allowed to play in a football game and the players let them score a touchdown, do they know it's just people being nice?

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β€œNearly 1/2 of Canadian crisis pregnancy centre websites claimed β€œPost-abortion Syndrome” β€” which has been countered by studies. In fact, research has found that while having an abortion is not linked to mental health issues, restricting abortion access is.” thediscourse.ca/vancouver…
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The Ketogenic Diet in the Treatment of Post-concussion Syndromeβ€”A Feasibility Study ncbi.nlm.nih.gov/pmc/arti…
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πŸ‘€︎ u/FraGough
πŸ“…︎ Mar 06
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Kiley has Williams Syndrome and sometimes has trouble making friends her age. She met the most amazing girls at church camp last summer, problem is they live 3 hours away. They call her everyday & make her feel so loved. This is them surprising her!!! v.redd.it/4qds7iqhmt491
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πŸ‘€︎ u/Thryloz
πŸ“…︎ Jun 10
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Isitbullshit: Marijuana’s only medical uses are treatment of Glaucoma and Wasting syndrome?

My stepdad is a addiction specialist/physiatrist and says the only uses of weed are to treat these 2 conditions. I doubt this as I’ve heard a multitude of benefits of medical cannabis but I’m confirming here I guess.

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A Study Protocol for an Open-Label Feasibility Treatment Trial of Visual Snow Syndrome With Transcranial Magnetic Stimulation frontiersin.org/articles/…
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πŸ‘€︎ u/TryggWinston
πŸ“…︎ Sep 27 2021
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Females far likelier to suffer with Long COVID, a new review of studies shows, underscoring a critical need for sex-disaggregated research: The odds of females developing Long COVID syndrome is 22% higher than males, researchers find sciencedaily.com/releases…
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πŸ“…︎ Jun 22
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Study: PTSD sufferers share bacterial footprint in saliva | Breakthrough research may help speedy diagnosis and treatment of people suffering from post-trauma. israel21c.org/study-ptsd-…
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πŸ“…︎ Aug 14
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Females far likelier to suffer with Long COVID, a new review of studies shows, underscoring a critical need for sex-disaggregated research: The odds of females developing Long COVID syndrome is 22% higher than males, researchers find sciencedaily.com/releases…
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πŸ‘€︎ u/EvanMcD3
πŸ“…︎ Jun 22
🚨︎ report
Genetics of irritable bowel syndrome: shifting gear via biobank-scale studies

https://www.nature.com/articles/s41575-022-00662-2.epdf?sharing_token=hriFpe2Y5R_BQTQy-jEJV9RgN0jAjWel9jnR3ZoTv0MBUkPNwf7tnbxdolPVCOemmgjUafIdCY6OtCqUUO9GHLP8FHbVqpGXces7SwlXJqljK3P9pfjAq62egn0T7lck7IyuiFEy-FUl8hZKfuQ1sOja_imhpnfhFQWnaYx_lu0%3D [Edit: New link with full text]

Key points

  • The pathophysiological mechanisms associated with irritable bowel syndrome (IBS) are only partially understood; this hampers the development of targeted therapeutic strategies.
  • Genetic research can reveal actionable pathways, but findings have generally been scarce in IBS because genetic investigations have been small scale and based on single-gene approaches that have highlighted only a few putative risk genes related to serotonergic mechanisms, carbohydrate digestion or ion channels.
  • Large-scale, biobank-wide genome-wide association studies (GWAS) that focused on IBS and endophenotypic proxies of gut motility have been reported, and have led to the identification of the first set of unequivocal risk loci.
  • These loci contain several genes relevant to pathways and cell types implicated in the central and enteric nervous system activities, neurotransmitter signalling and enteric motor neuron function; these findings offer avenues for testing novel therapeutic strategies.
  • The genetic architecture of IBS identified to date through GWAS often seems to be shared with comorbid mood disorders and anxiety, which is consistent with the reported efficacy of psychotropic and cognitive therapies in IBS.
  • Polygenic scores derived from GWAS data enabled the identification of individuals at increased risk of IBS in the studied cohorts and could be further refined and validated in independent translational studies.

The pathophysiology of irritable bowel syndrome (IBS) is multifactorial and probably involves genetic predisposition and the effect of environmental factors. Unlike other gastrointestinal diseases with a heritable component, genetic research in IBS has been scarce and mostly characterized by small underpowered studies, leading to inconclusive results. The availability of genomic and health-related data from large international c

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πŸ‘€︎ u/jmct16
πŸ“…︎ Aug 10
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my baby with suspected Williams syndrome!
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πŸ“°︎ r/williamssyndrome
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πŸ“…︎ Aug 08
🚨︎ report
Study finds new Treatment that neutralizes all COVID-19 variants : Monoclonal antibody SW186 can neutralize all SARS-CoV-2 variants of concern, including Omicron subvariants, and SARS-CoV-1. science.org/doi/10.1126/s…
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πŸ“°︎ r/science
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πŸ“…︎ Aug 07
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Ramsay Hunt syndrome following COVID- 19 vaccination. Could Justin Bieber's case also be a vaccine side effect? Preclinical studies supported remedies.

A paper published in BMJ, late last year, from the University of Hong Kong, documented a case of Ramsay Hunt syndrome (RHS) following COVID-19Β vaccination. Below is a snippet from the study, with details about the case and the possible etiology following the vaccination, along with rationale for why some Bell's Palsy cases, which were observed more frequently than RHS following the vaccine could actually be misdiagnosed RHS cases:

>We recently diagnosed Ramsay Hunt syndrome (RHS) in a 37- year- old previously healthy man. Two days after his first dose of the Pfizer- BioNTech (BNT162b2) vaccine, he noticed fever and a pain in the right ear. Vesicles were then developed in his right ear and canal, together with vertigo, tinnitus and loss of hearing. He complained of facial palsy, tongue numbness and dysgeusia. On examination, he had grade 4 right facial nerve palsy of the lower motor neuron type with right sensorineural hearing loss (figure 1A). There were no other neurological deficits. Vesicles with serous discharge were found over the right concha and external auditory canal (figure 1B). A swab of the exudate was positive for varicella- zoster DNA on PCR, while throat saliva was negative for SARS- COV- 2. A CT scan of the brain was normal. The diagnosis was RHS leading to peripheral facial nerve palsy, vestibulocochlear neuropathy and glossopharyngeal somatic sensory neuropathy. As his symptoms developed 2 days after vaccination, we suspected the vaccination triggered RHS. This would be the first reported case of RHS after COVID- 19 vaccination.

>Bell’s palsy is the most common cause of an acute onset peripheral facial palsy. Some cases were attributed to the reactivation of herpes- simplex virus (HSV) and varicella- zoster virus (VZV). The former is always underdiagnosed. However, the blisters of herpes zoster (HZ) allow a diagnosis to be made clinically. Reactivation of the VZV at the facial nerve leads to RHS type 2 (herpes- zoster oticus). However, there are also cases where RHS may manifest without the skin lesions such that it cannot be differentiated from Bell’s palsy without PCR or antibody titre testing.3

>HZ is associated with COVID- 19 vaccination. The US Vaccine Adverse Event Reporting System (VAERS) reported 232 HZ- related adverse events among COVID- 19 vaccines among 1653 reports of vaccine- related complications since July 1990. All reported cases so far affected other dermato

... keep reading on reddit ➑

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πŸ“…︎ Jun 13
🚨︎ report
I call this "study abroad syndrome" or "I've never actually bothered to look outside one aisle" youtu.be/FovIyqov1uA
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πŸ“°︎ r/iamveryculinary
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πŸ‘€︎ u/laughingmeeses
πŸ“…︎ Jul 17
🚨︎ report
TIL neurofeedback, a technique teaching control of one’s brain activity, is still controversial due to inconsistent results, even in double blinded studies, despite it being around for decades. All these didn’t stop private neurofeedback clinics from selling this treatment to patients. neurofrontiers.blog/neuro…
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πŸ‘€︎ u/atat_sa_putut
πŸ“…︎ Aug 14
🚨︎ report
New target identified for treatment of premature aging disease: Scientists have found that blocking the RNA known as LINE-1, reverses the effects of Progeroid syndromes, which include Hutchinson-Gilford progeria syndrome and Werner syndrome, which causes accelerated aging in children. science.org/doi/10.1126/s…
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🚨︎ report
Why are all NSAIDs (except aspirin) contraindicated in peri-infarction pericarditis, while they are the mainstay of treatment in Dressler's syndrome?
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πŸ“°︎ r/Step2
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πŸ“…︎ Aug 08
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Great news, Triall is helping researchers study a new treatment for Irritable Bowel Syndrome (IBS) learn more from the link below twitter.com/triallofficia…
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πŸ‘€︎ u/Judyke
πŸ“…︎ Jul 25 2021
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Networks Are Associated With Acupuncture Treatment in Patients With Diarrhea-Predominant Irritable Bowel Syndrome: A Resting-State Imaging Study pubmed.ncbi.nlm.nih.gov/3…
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πŸ‘€︎ u/ShenNong8
πŸ“…︎ Nov 04 2021
🚨︎ report
Randomised clinical trial and meta-analysis: mesalazine treatment in irritable bowel syndrome-Effects on gastrointestinal symptoms and rectal biomarkers of immune activity

https://onlinelibrary.wiley.com/doi/10.1111/apt.17182

Abstract

Background: Low-grade immune activation in the gut is a potential treatment target in irritable bowel syndrome (IBS).

Aims: To determine improvement in IBS symptoms after mesalazine treatment, and the utility of measures of immune activity in the rectal mucosa METHODS: This was a randomised, double-blind, placebo-controlled, parallel-arm, multicentre trial in subjects with IBS (Rome III criteria), with an eight-week treatment period of mesalazine 2400 mg or plcebo once-daily. The primary endpoint was the global assessment of satisfactory relief of IBS symptoms in β‰₯50% of weeks during intervention. IBS symptoms were also measured with the IBS severity scoring system; immune activity was measured by mucosal patch technology. A post hoc meta-analysis of randomised placebo-controlled trials of mesalazine in IBS was added.

Results: Of 181 included patients, 91 received mesalazine and 90 received placebo. The primary endpoint was met by 32 (36%) patients after mesalazine and 27 (30%) after placebo (p = 0.40). There were no differences in response rates related to IBS subtype or post-infection symptom onset. More reduction of abdominal bloating was noted in the mesalazine group (p = 0.02). The meta-analysis showed no effect of mesalazine on IBS symptoms. No mucosal patch technology measure could predict response to mesalazine, and found no differences in the effects of intervention on levels of immune markers.

Conclusions: Mesalazine is ineffective in reducing IBS symptoms. Rectal measures of immune activity by the mucosal patch technology cannot predict a higher chance of response to mesalazine.

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πŸ‘€︎ u/jmct16
πŸ“…︎ Aug 09
🚨︎ report
Successful Treatment of Hard Flaccid Syndrome: A case report
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πŸ“°︎ r/Hard_Flaccid
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πŸ‘€︎ u/nathanpalme123
πŸ“…︎ Aug 06
🚨︎ report
New research in people with metabolic syndrome has shown that consuming green tea extract for 4 weeks can reduce blood sugar levels and improve gut health by lowering inflammation and decreasing β€œleaky gut.” The daily dose, made into a gummy candy for the study, equaled 5 cups of green tea. news.osu.edu/green-tea-ex…
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πŸ‘€︎ u/memorialmonorail
πŸ“…︎ Jul 26
🚨︎ report
Does anyone have restless leg syndrome? Is there any treatment?

I am struggling with RLS since young and sometimes it comes and goes. I have no idea how to describe the feeling of having restless legs. It feels irritating? It can also occur at any time of the day. When it strikes day time, I have the strong urge to move a lot and shake my legs violently but it is not nice to be shaking your legs in a meeting. During night time, it affects my sleep a lot as any position is uncomfortable. Taking the plane is the worst as you cannot move much. If you have RLS, please share your experience and how you cope with it!

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πŸ“°︎ r/askSingapore
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πŸ‘€︎ u/kubbito
πŸ“…︎ Jul 29
🚨︎ report
31, single, Raynauds syndrome, my Bible study group is down to just 3, Why did people stop coming?
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πŸ“°︎ r/RoastMe
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πŸ‘€︎ u/jthrowawaymc
πŸ“…︎ Jun 29
🚨︎ report
Monitoring treatment harm in myalgic encephalomyelitis/chronic fatigue syndrome: A freedom-of-information study of National Health Service specialist centres in England - Graham McPhee, Adrian Baldwin, Tom Kindlon, Brian M Hughes, 2021 journals.sagepub.com/doi/…
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πŸ“°︎ r/cfs
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πŸ‘€︎ u/CFSJames
πŸ“…︎ Sep 09 2021
🚨︎ report
Off label use of Aripiprazole shows promise as a treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a retrospective study of 101 patients treated with a low dose of Aripiprazole | Journal of Translational Medicine translational-medicine.bi…
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πŸ“°︎ r/cfs
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πŸ“…︎ Feb 04 2021
🚨︎ report
Mirrored-self misidentification (MSM) is a rare phenomenon observed in delusional misidentification syndrome. People with MSM believe that their own mirror image is another person. Here a case study by Rong et al. (2020) is described. youtu.be/MF2KyYEUZTE
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πŸ“°︎ r/psychology
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πŸ‘€︎ u/AdMysterious1930
πŸ“…︎ Jul 31
🚨︎ report
A possible treatment for visual snow syndrome - noninvasive vagus nerve stimulation ?

A possible treatment for visual snow syndrome - noninvasive vagus nerve stimulation ?

https://3002a505d4f8666b1f13-6d0524d9c8a5052ce15209ae3ecb39a3.ssl.cf1.rackcdn.com//1331552-1590438434.pdf

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πŸ“°︎ r/visualsnow
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πŸ“…︎ Aug 10
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