Ok, so I'm conceptualizing an alien planet for a hypothetical storyline in which a human is transported halfway across the universe John Carter-style. I was planning on having the atmosphere being composed with a higher percentage of oxygen (around 40 to 50%). I did some research, and I found some conflicting articles, but I think my main takeaway is that the human traveller would have higher endurance and stamina for the first day or two before beginning to succumb to oxygen toxicity, which would start to slowly kill him. Now that I've created a problem, I have to figure out how to solve it in-universe. However, I can't seem to find anything that would reverse the effects, and most treatments for oxygen poisoning boils down to "breathe normal air", which isn't exactly a possibility on an alien planet. So yeah, sorry for rambling on, but if someone could help me out I'd appreciate it. Sorry if this doesn't fall under worldbuilding by the way.
This is a hypothetical question as obviously what limits us diving to deep depths is the pressure exerted on our lungs and with scuba gear the likes of oxygen toxicity plays a factor, but if these factors were removed, how deep could a human body go before being literally crushed by deep ocean pressure?
It is said that if the human body gets too much oxygen the cells get damaged and start to die. How exactly does more oxygen in the body cause this? And if this is so harmful, how do HALO skydivers breath this in 30-45 minutes before the dive without any I'll effects?
My grandma recently started requiring supplemental oxygen at home and the nurse told my family to ensure her SP02 isn’t maintained for long periods of time over 95% because this can lead to oxygen toxicity. She is on a medical grade oxygen concentrator which I have read provides approximately 90-95% pure oxygen. (She uses 1-2 concentrators to provide 4-10lpm as needed to maintain SP02 between 90-95%) How does oxygen toxicity work and how quickly can it occur in a situation like this? Articles I have found online are a bit over my head. Thanks!
I’m a PADI Enriched Air instructor and am currently working through my TDI Advanced Nitrox and Decompression Procedures courses, so I have a fairly decent understanding of PPO2’s and oxygen toxicity. But I was talking to someone who works records at a hyperbaric medicine facility and she was telling me they frequently send people to PPO2’s in the chamber that (based on all of my SCUBA knowledge) would most likely send a diver into convulsions if they went to the equivalent depth. I understand that the recommended PPO2’s we follow are widely variable based on a variety of factors, but can anyone help me to understand why a person “diving” in a chamber won’t convulse while a person actually diving to equivalent depth breathing 100% O2 is likely to?
The use of the paraglider in BOTW is indicative of a much higher air density than that of Earth's. Consider Link falling straight downwards with the paraglider out: since Link falls at a constant speed the resultant force on him must be 0 Newtons, thus Link's weight must be equal to the force caused by the air resisting the movement of the paraglider. Since F=(change in momentum)/time, and change in momentum per second=volume of air the glider traps per second x density of the air x velocity of the glider, working through the equation and substituting F=W produces the result: velocity^2 x (area of glider) x density = Link's weight. Therefore the density of the air in BOTW = (Link's weight)/(velocity^2 x area of the glider). Even substituting the smallest values guessed for Link's weight and largest values for the falling velocity and area of the glider, to reach the smallest value for the density of the air reaches a value over 20kgm^-3, for comparison the average density of air at sea level on Earth is 1.225kgm^-3. Air of this high a density will in turn lead to a much higher air pressure, since air pressure is proportional to air density, so the air pressure in BOTW would be roughly 20x our own. High air pressures would cause excess oxygen and nitrogen to be forced into the bloodstream at the alveoli, which would cause hyperoxia. An initial symptom of hyperoxia is grand-mal seizures, and in time it causes death.
I underwent BEP chemo this year. My doctors never told me about the risk of oxygen toxicity or pulmonary fibrosis associated with bleomycin. I learned by researching it myself.
My GP wants to try oxygen for my cluster headaches (starting at 2 liters). I remembered the possibility for oxygen toxicity during anesthesia, so I put a message in to my oncologist to ask if it was okay. The message came back: no oxygen ever. room air only.
Now I'm conflicted. If it was this serious, I would think he would have warned me about it. Especially when I was the type of patient that pushed him for every little side effect or danger. Two liters isn't even that much oxygen (something like 28% I believe). The studies I've seen recommend room air or slightly higher when going under anesthesia. I've also seen different numbers on how many are affected (10% to 30%).
Anybody else have experience with bleomycin and oxygen toxicity? What did you hear from your doctors? I'll be talking to both of my doctors again before I actually use the oxygen (and if I can, an anesthesiologist).
Edit: Talked with a bone marrow transplant doc (as they potentially want to look at this for me). He said he wouldn't even worry about 2 liters (being as it is such a low percentage of oxygen). He said even higher than that is fine, and only to worry about it if I was ever going under. If that happened, I should inform the anesthesiologist and have him put me on the lowest safe amount of oxygen. My lungs are also pretty fine. I know there is some scarring and fibrosis in there, but not too bad. I'll be doing another pulmonary function test soon (ordered by him) just to have a before and after comparison. Unfortunately I'll also be doing some more chemo soon.
Let me start with saying I am not, and have never been, a medical student. I write fantasy but I do like to maintain some realism, so if any of you can help me with a practical question I'd be grateful. And I apologize ahead of time for any accidental misuse of terms or if this is not the right forum for such a question.
I've been researching oxygen toxicity and head trauma independently and have a passing grasp of symptoms, ill-effects, etc, and would like to fact-check what might occur if they were to happen concurrently.
The scenario plays out thus:
-Girl in otherwise good health is exposed to pure oxygen shortly before an explosion; she begins to suffer early symptoms of oxygen toxicity (myopia, disorientation, etc)
-Explosion throws girl back and she lands hard with her head on stone, causing major head trauma/edema
-Rescued after a short period of continued exposure to pure oxygen (as of right now the oxygen is at normal to slightly high pressure)
-She develops partial paralysis on the right side of the body immediately after the injury
My question at the moment is whether she would likely require surgery to relieve the pressure on her brain, or if the exposure to pure oxygen might actually assist with relieving pressure:
As I understand it in layman's terms, exposure to pure oxygen causes the blood vessels to constrict and can be used as therapy in the event of torn blood vessels. If the character in question were to experience trauma-related edema and oxygen toxicity concurrently, could there be a positive outcome as far as the oxygen relieving pressure on the brain and reducing the need for surgery, or is it more likely that the ill-effects of the oxygen would outweigh the potential benefit/compound the brain injury?
Or in the event of edema, would the effects of pure oxygen be too minor to make a real impact?
The story itself is not a medical drama, but I'd like to at least get the details right when they appear instead of glossing them over. Thanks for reading--any info or articles you care to post are much appreciated.
I forgot the username. I forgot the sub-reddit's name. Luckily, I wrote down a bit of his/her post. I searched it on google, nothing. I searched it in reddit, nothing.
can anyone link me to the original post?
here is his / her post:
because oxygen is very very bad for you. Oxygen is incredibly reactive, chemically speaking. That's why oxides are so common. Rust is the spontaneous formation of iron oxide on the surface of ferrous objects. It's also extremely soluble in water, which means molecular oxygen gas dissolves readily in anything made of water ... including you.
Having too much oxygen in your body is what the whitecoats call "hyperoxia," and it's incredibly dangerous. Different parts of your body react to excess oxygen in different ways, all of them bad. It induces haemolysis, which is the spontaneous self-destruction of red blood cells. It damages your liver and your kidneys. It damages your retinas and can result in blindness. It interferes with your cellular metabolism and homeostasis, causing acidosis. It damages your mucus membranes and pulmonary tissues, causing oedema which, ironically, leads to hypoxaemia: you can literally suffocate to death in a pure-oxygen environment. And the havoc excess oxygen wreaks on your central nervous system cannot be overestimated, causing convulsions, destruction neurons, and disrupting your nervous system to the point where you just spontaneously die.
Oxygen is actually incredibly toxic. If I locked you into a room filled with pure oxygen at sea-level pressure, you'd be in agony in hours, and dead in no more than a couple of days. Sent from my BlackBerry 10 smartphone on the