Probiotics that make neurotransmitters.
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πŸ‘€︎ u/Madeupusernames
πŸ“…︎ Jan 23
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If mental illness like psychosis is a chemical imbalance or or a problem in neurotransmitters, what happens in a schizophrenic’s sleep, why does the schizophrenia become β€œdeactivated” and lets a person sleep because he or she β€œdoesn’t”have symptoms in their sleep?

What happens to the neurotransmitters/chemicals in the brain when a person sleeps vs when they’re awake with a mental illness like schizophrenia/psychosis? Why doesn’t the illness bother them in their sleep?

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πŸ‘€︎ u/notadoc0014
πŸ“…︎ Mar 09
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If fibro is neurotransmitter dysfunction

Why are we cared for by rheumatologists and not neurologists? Or maybe you are cared for by a neurologist? Who is the best provider to care for this condition? Appreciate your insight/experience

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πŸ“°︎ r/Fibromyalgia
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πŸ‘€︎ u/CharismaTurtle
πŸ“…︎ Mar 09
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Structures of Neurotransmitters
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πŸ‘€︎ u/gazer2001
πŸ“…︎ Mar 10
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Does C19 Vaccine impact neurotransmitters? (Cortisol, Adrenaline, etc)

Has anyone seen any literature on this or is this a reach?

I started thinking about how varied everyone’s vaccine response has been - and also some of the things people have been complaining about: high anxiety, GI issues, tingling, insomnia, etc. <<<< these are also very similar to what happens when your neurotransmitters are off (high cortisol, adrenaline, serotonin, etc). I wonder if they are at all related? If so, it may help with how we can best manage rough side effects.

Let me know what you think!

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πŸ“°︎ r/CovidVaccinated
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πŸ‘€︎ u/DetroitNYC
πŸ“…︎ Mar 08
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We are all just neurotransmitters
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πŸ“°︎ r/tumblr
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πŸ‘€︎ u/franticallyaspaz
πŸ“…︎ Jan 27
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Can someone explain how exactly this condition makes my mental health so bad? Do we not produce serotonin, does it impair our brains neurotransmitters?

Any info is appreciated.

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πŸ“°︎ r/Hashimotos
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πŸ‘€︎ u/Ok_Metal_3947
πŸ“…︎ Mar 05
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Debunk This:Frequent masturbation is bad for you because you stimulate neurotransmitters ,The more you stimulate them by masturbating, the less you produce them, which is exactly what happens if you use drugs regularly.

I found this in a comment on a Psychology today article about you guessed it masturbation Link here

>Yes, frequent masturbation is bad for you. Each time you masturbate you are stimulating your neurotransmitters in an artificial way, similar to drugs or any substance that is not a natural food. The more you stimulate these neurotransmitters by masturbating, the less you produce them, which is exactly what happens if you use drugs regularly. When these neurotransmitters are out of balance, you are not yourself and you become weak and meager in your mind. That masturbation is harmless is a lie perpetuated by people that want to keep you enslaved in a world where you do not have the mental faculties to see the truth or stand up for yourself. Stop making excuses for jerking off and start waking up to the truth!

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πŸ“°︎ r/DebunkThis
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πŸ“…︎ Mar 03
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Parnate and release of neurotransmitters

At what dose does parnate start releasing dopamine and norepinephrine?

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πŸ“°︎ r/MAOIs
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πŸ“…︎ Mar 07
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Wait, it was all just neurotransmitters and axons? Always has been
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πŸ“°︎ r/memes
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πŸ“…︎ Mar 07
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Anhedonia, Neurotransmitters, and You

Anhedonia

β€œTHE DISEASE WAS LIFE ITSELF … You realize all this ... when you look at the black hole and it's wearing your face.” - David Foster Wallace

First of all, if you’re reading this, I feel for you. And not in the sympathetic, β€œeverything’s gonna be ok” kind of cliches that our culture parrots to avoid answering tough existential questions. Total anhedonia is one of the worst things a human being can possibly experience, and I wouldn’t wish it on my worst enemy. If you’ve ever truly experienced this, I’m sure you’ll know where I’m coming from. When left unchecked, anhedonic depression quickly becomes a terminal illness. In writing this post, I sought to gather as much information as possible from my own experience and the scientific knowledge available to find some hope of recovery, or at the very least, some answers.

Doing this research was both enlightening and terrifying for me. It may be the negativity bias of people who post their anecdotal experience on the internet (fully recovered cases have less of an incentive to post?), but if anything knowing about the mechanisms of every antidepressant available and how, for some people, none of them will help, is quite disheartening. It seems to me that time is the number one factor in healing from most depression and is a likely confounding variable behind the success rates of medications.

Depression as it relates to anhedonia, as far as I conceptualize it, can fall into either one of these categories, or somewhere in-between.

(1 - Exogenous) Cases that are produced by external environmental factors / easily fixable lifestyle problems will often resolve permanently *with or without medication* when the person takes necessary steps to change. Medication like SSRIs in these cases can offset anxiety and reduce some symptoms like guilt / rumination until the episode passes naturally, but don’t help with anhedonia.

(2 - Endogenous) Cases where anhedonia is the core symptom are often chronic sufferers of depression, where medications like SSRIs can help to reduce some symptoms and prevent suicide, but don’t fix the core problem of anhedonia. If anything has become clear to me through this research, it’s that anhedonia is the single symptom that modern treatments have no consistency in treating.

My hope for myself is that my case is more like the first than the second, although I often struggle to believe that. A big point of confusion for me throughout this whole experience has been the fact that

... keep reading on reddit ➑

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πŸ“°︎ r/anhedonia
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πŸ‘€︎ u/TheScientist_Wink
πŸ“…︎ Jan 22
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Depression: Die MΓ€r vom GlΓΌckshormon β€” Die meisten Antidepressiva zielen darauf ab, die Konzentration des Neurotransmitters Serotonin im Gehirn zu erhΓΆhen. Dass die Mittel bei vielen Patienten wirken, kΓΆnnte aber ganz andere GrΓΌnde haben spektrum.de/news/depressi…
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πŸ“°︎ r/de
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πŸ‘€︎ u/localhorst
πŸ“…︎ Dec 15 2020
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Acetylcholine, as a neurotransmitter, indicates that the subject is dreaming. Campaigns like this would be the norm if Shakespeare's "A Midsummer Night's Dream" happened today.
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πŸ‘€︎ u/Myracast
πŸ“…︎ Feb 24
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Paleocon discovers neurotransmitters, thinks it’s slavery

https://preview.redd.it/qh2n986smtl61.jpg?width=1536&format=pjpg&auto=webp&s=1b69963d1041981dfacd5c090947d337e57a11ac

https://preview.redd.it/2nlhhg6smtl61.jpg?width=1536&format=pjpg&auto=webp&s=4d36278341cee290b0a99fde7e3b7d5faee38579

https://preview.redd.it/qbytmd6smtl61.jpg?width=1536&format=pjpg&auto=webp&s=4636bdc5f9a8443a842475e6bf4306d1c2835948

https://preview.redd.it/012wcl6smtl61.jpg?width=1536&format=pjpg&auto=webp&s=ecd3a5e29eee8026a01473bcb314460735f851fd

https://preview.redd.it/k2l5w37smtl61.jpg?width=1536&format=pjpg&auto=webp&s=9b4b233256f96952786a6820fea963f7ec2d28f0

https://preview.redd.it/b2n6fa7smtl61.jpg?width=1536&format=pjpg&auto=webp&s=29bf427b37435ee09343a2a7be4957e25c30858b

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πŸ“°︎ r/Fuckthealtright
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πŸ‘€︎ u/anfal857
πŸ“…︎ Mar 08
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Organic Acids Test (measuring neurotransmitters)

I'm on Trintellix and haven't had much success. My anxiety is so physical and difficult to manage.

My desperation took me to a Naturpath. He's ordered a Organic Acids Test, which he claims can measure neurotransmitters and give a clearer picture on my gut and brain health...which in turn could be effecting my anxiety.

Anyone here had one of these tests? Can it give a clearer picture on which antidepressant I need?

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πŸ“°︎ r/antidepressants
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πŸ“…︎ Mar 07
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Articles about strattera causing permanent gene alterations and liver/neurotransmitter damage? Wtf

I read too much on the internet and as the title says, I read that strattera left some people unhappy, depressed, and even with permanently impaired cognitive function once they got off of it. I have mild adhd and my doctor prescribed me 25mg a day. Should I be scared? Words of reassurance/ truth would be nice

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πŸ“°︎ r/ADHD
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πŸ‘€︎ u/celium04
πŸ“…︎ Feb 25
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At death your brain has a burst of activity, as dying cells release stored neurotransmitters. Time dilation makes the process of dying feel like it lasts forever. Whether you experience this eternity as sheer bliss, absolute anguish or something in between depends on the state of your conscience.

That's all, enjoy your day.

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πŸ“°︎ r/Psychonaut
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πŸ“…︎ Nov 03 2020
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BRAIN NEUROTRANSMITTER: [OFF] v.redd.it/0e7v7nr9g0m61
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πŸ“°︎ r/EscapefromTarkov
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πŸ‘€︎ u/mannysnook
πŸ“…︎ Mar 09
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Neurotransmitter Tracking???

Just curious if there’s anyway of doing so yet... Primarily dopamine, but really any of the main ones...

Serotonin, oxytocin,acetylcholine, norepinephrine, GABA, glutamate...

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πŸ“°︎ r/QuantifiedSelf
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πŸ‘€︎ u/Hippie-Magic
πŸ“…︎ Feb 09
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ELI5: How do neurotransmitters get to your nerves? Like, where are they the rest of the time and what sends them to a nerve and how and where do they go?
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πŸ‘€︎ u/jamescmcneal
πŸ“…︎ Jan 22
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Synthesis of neurotransmitters

Dear community,

For a school project I wanted to synthesize some neurotransmitters. The paper would consist of the chemistry part and then a theoretical part on how they are made in the human body and what they do.

I’ve looked up for example the reaction for seratonin from tryptophan and it seems easy, as it is just a two part reaction. HOWEVER, I’ve only found the reaction that happens in the body with enzymes. I am sure it has to be possible to do it yourself as the reaction consists of hydroxilation and decarboxilation.

Do you think it is a reasonable goal for a chemistry beginner to try this task?

Thanks for your answers

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πŸ“°︎ r/chemistry
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πŸ“…︎ Feb 11
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Streak 10: Neurotransmitters

Have you ever thought about how our brains are work? Yes, there are billions of neurons and other type of cells in our brain. But how do they work and how are thoughts created by them? The answer is very complicated. There are many mysteries about the work of the brain. We haven't figured all of them out yet. But scientists have found the chemical messengers. They are called neurotransmitters. And today I will describe a few of them in this post.

Serotonin: I think, this is the most popular neuratransmitter. People know this neurotransmitter as a happiness hormone. But happiness is a complicated situtation, in my opinion it's like a chemical soup so only this neurotransmitter is not sufficient to be happy.

Dopamine: This neuratransmitter is the reason of feeling aware, and excitement. When you do an evolutionary good thing such as eating something very nutritious, having sex etc. your brain give you this reward. And this mechanism also causes to addiction when it is abused.

Adrenaline: Neurotransmitter of fight or flight response. When you see a predator, this hormone prepare yourself to run. This hormone also can give you unbelievable power. You can have superhuman strength with this hormone for a short time.

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πŸ“°︎ r/WriteStreakEN
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πŸ‘€︎ u/physiolover
πŸ“…︎ Feb 17
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ELI5: Why can't neurons just form physical connections as in reticulate theory instead of using neurotransmitters?

why do they do the extra work to make neurotransmitters, convert electrical impulses into chemical then have neurotransmitters bind and then conversion into electrical again? Couldn't they just connect with each other like other cells form a tissue as the reticulate theory suggested? Are there any advantages to this extra effort or is it just another lack of efficiency?

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πŸ‘€︎ u/chauhan_14
πŸ“…︎ Feb 08
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Braverman neurotransmitter personality test

Has anyone taken the Braverman personality test based on neurotransmitters? The few NFs I know have all gotten acetylcholine dominant. Someone pointed out the role of this neurotransmitter in schizophrenia, which would corroborate my hypothesis that us NF have the highest risk of schizophrenia.

In case you are interested too, here is the test (there's a captcha front page)
https://www.bravermantest.com/

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πŸ“°︎ r/infj
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πŸ‘€︎ u/ahlearning
πŸ“…︎ Dec 26 2020
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Long term use of choline supplements or other neurotransmitter effecting nootropics

I’d really like to know if there is any evidence, or experience on the long term effects of nootropics or supplements that cause changes in neurotransmitters.

Well I’ve searched the internet, and read what I can find but I have no real answers. I imagine that using substances -like alpha-gpc for example- that directly affect neurotransmitters would have a long term sort of what goes up must come down effect. Meaning that if someone took a choline supplement like alpha-gpc for extended periods over some amount of years, that in turn they would no longer have a proper autonomous regulation of acetylcholine.

I suspect similar things must happen with gaba after long term use of things like benzodiazepines, alcohol, or phenibut.

I’ve read that noopept can be a strong neuroprotectant by helping regulate glutamate. Which only makes me more curious here.

Am I not looking hard enough, should I be able to figure this out on my own with better knowledge of the brain? Thank you!

To put quite simply, I’d like to know if a lizard took smart drugs taken for long periods of time would that later make the lizard stupid.

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πŸ“°︎ r/Nootropics
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πŸ‘€︎ u/pigeonmyst
πŸ“…︎ Jan 18
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A functional logic for neurotransmitter co-release in the cholinergic forebrain pathway biorxiv.org/content/10.11…
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πŸ“°︎ r/BiologyPreprints
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πŸ‘€︎ u/sburgess86
πŸ“…︎ Feb 26
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Get essential neurotransmitters NOW
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πŸ“°︎ r/memes
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πŸ‘€︎ u/Lalakhalid
πŸ“…︎ Dec 26 2020
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Any thoughts? This sea of red mao-as can't be good right? I have brain fog/neurotransmitter issues.
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πŸ“°︎ r/MTHFR
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πŸ‘€︎ u/irinseit
πŸ“…︎ Feb 11
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Neurotransmitters are the physical manifestation of consciousness.

Hear me out.

Most living things contain at least some trace amounts of DMT. Serotonin is pretty common as well and very closely related.

I’ve been thinking about what connects all living things here in the physical realm while also potentially preserving the perspective of being separate, and it occurred to me that particularly DMT might be the physical manifestation of consciousness itself.

Within all of these different living bodies with unique and differentiated systems and modes of operation, the DMT can experience itself in many different iterations.

The relative levels of DMT you might find in various organisms relate to their level of consciousness (which I would say can differ greatly from sentience & intelligence).

Pure consciousness doesn’t need to think, it just is.

You could argue that the reason it feels like DMT is a portal to the universal consciousness is because we’re giving the substance a framework to process and to some extent, store information itself.

It becomes more obvious that our brain isn’t the origin of consciousness itself because information and even thought processes to some degree can occur on machines. The thing that colors the thought processes and the memories and actions, etc., are your neurotransmitters. They’re the object and motivation of every action we take. Maybe they’re not just the reward for our actions, maybe our bodies exist to act as efficient vessels to collect and regulate them at different densities.

This isn’t as well articulated as I would like it to be because it’s late and I’m tired, but I still feel pretty confident that at some point we will need to account for the linkage between physical and metaphysical realms while maintaining some kind of framework for the origin of consciousness.

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πŸ“°︎ r/DMT
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πŸ‘€︎ u/void_slinger
πŸ“…︎ Feb 05
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The most comprehensive methylation, detox, and neurotransmitter synthesis illustration I've ever seen + a link to comprehensive biochemical pathways map!

Came across this looking for what cofactors are needed for which enzymes and came across this gem! I just had to share!

Best Map Ever

Also, If you would like to take a look at how the body's pathways interact or just learn more about biochemical pathways, here's a link to a very detailed look at the intricacy of the body's biochemistry.

http://biochemical-pathways.com/#/map/1

Enjoy!

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πŸ“°︎ r/MTHFR
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πŸ‘€︎ u/H_Elizabeth111
πŸ“…︎ Jan 11
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Neurotransmitters Studies..?

Looking around how Ssri work or any other symptoms related to mental health leading me to that its related to chemicals imbalance in the brain, so i was looking more about neurotransmitters and found out that there is no test for knowing neurotransmitters balance

so i was thinking if there is no way to look about neurotransmitters than how so science and doctors came to know a lot of about neurotransmitters detail....i mean from where they have studied neurotransmission of brain if there is no way to look in it...?

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πŸ“°︎ r/PSSD
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πŸ“…︎ Jan 21
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More evidence for pepcid+cetirizine+antihistamine diet. "Histamine acts as an excitatory neurotransmitter in the brain. The body naturally releases the most histamine around 3 am. And if your histamine stores are already too high, this can wake you up in the middle of the night"

https://mastcell360.com/fixing-sleep-challenges-in-mast-cell-activation-syndrome-and-histamine-intolerance/

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πŸ“°︎ r/covidlonghaulers
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πŸ‘€︎ u/Fkkcvv
πŸ“…︎ Jan 28
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Are there any strains that are known to boost production of the neurotransmitters dopamine and serotonin?

That is, neurotransmitters in the brain. We know that dopamine and serotonin created outside the CNS cannot cross the BBB.

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πŸ“°︎ r/Microbiome
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πŸ‘€︎ u/Liberated051816
πŸ“…︎ Jan 24
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ELI5: If our bodies get desensitized by neurotransmitters, requiring larger doses to get the same effect, why does the neurotransmitters our body releases during sleep to paralize us never stop working?

It is wide spread that if we are getting doses of serotonin we will end up requiring more and more to have the same effect in the long run because the brain has a mechanism to adjust for the doses it is getting. This is a problem for recreational drug usage because it can get to a point where the required dose will exceed the toxic and deadly level of consumption.

But I also know that when you sleep your body releases chemicals to regulate sleep. And some are serotonin, dopamine, GABA... neurotransmitters that in the context of drug usage are the same that the body will get desensitized from.

So why can we always sleep? What is the basic difference here?

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πŸ‘€︎ u/mvpetri
πŸ“…︎ Dec 27 2020
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How do antipsychiatrics work? Beyond the neurotransmitter mechanism

As title. Caveat, I've never had a job in psychiatry, my question is pretty layman as I have only just graduated medicine, working in the UK.

But I would be prescribing SSRIs as a junior GP. If it were moderate depression (based on ICD criteria I think) or above, NICE guidelines dictate that I should offer an SSRI, I'd plump with sertraline usually, and sometimes mutter something about chemical imbalance... and I knew that studies had shown benefit.

But, I never really knew how/why they improved depression, surely by boosting mood? I understand the neurotransmitter/synapse malarkey, but how does this translate downstream to actually improve a patients depression? Does more serotonin = less depressed? I can't help but think it's more complex than that.

I then wondered, if it is proven to improve mood, motivation, sleep - yknow all the depression symptoms we prescribe it for... Then could it be used as a nootropic?

Forgive my ignorance, I've never tried antidepressants.

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πŸ“°︎ r/AskPsychiatry
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πŸ‘€︎ u/CleverKnapkins
πŸ“…︎ Jan 09
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Does marihuana affects the neurogenesis of the neurotransmitters after quitting opioid/anfetamine addiction?

I quit opioid/anfetamine addiction 3 months ago. I've experienced a slow progress in feeling my neurotransmitters coming back to normality, specially dopamine. I know weed can affect mental clarity, motivation, energy levels and the daily use can compromise the reward system. But if I smoke 2 times a week it affects the brain's neurogenesis process to restructure the neurotransmitters? or it can possibly help?

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πŸ“°︎ r/AskDrugNerds
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πŸ‘€︎ u/TruthSeeker_199
πŸ“…︎ Dec 17 2020
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DMT Quest Documentary (featuring 3 ground-breaking discoveries from 2019 and the Wim Hof method for possibly increasing endogenous DMT via the DMT neurotransmitter system) youtu.be/My95s6ZryPg
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πŸ“°︎ r/microdosing
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πŸ‘€︎ u/NeuronsToNirvana
πŸ“…︎ Jan 28
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Study shows that a neurotransmitter produced by gut bacteria controls food preferences in its nematode host snippetscience.com/a-neur…
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πŸ‘€︎ u/adearman91
πŸ“…︎ Oct 14 2020
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How do Adderall and Wellbutrin target the same neurotransmitters yet produce different effects?

I hope this is the right place to post. I’m searching for a more scientific answer than what I’ve been able to piece together on the web.

From my understanding, Adderall (amphetamine/dextroamphetamine) and Wellbutrin (bupropion) both target norepinephrine and dopamine in the brain. Wellbutrin, an NDRI, inhibits the reuptake of those neurotransmitters, so they remain in the synapses between neurons for a longer duration before being reabsorbed. Most of the articles I’ve read regarding Adderall, a stimulant, either broadly state that the drug β€œtargets” or β€œincreases the availability” of those neurotransmitters, or describe the exact same process as an NDRI.

Here’s my rambling series of questions then:

Why do the two drugs produce different effects? Why is it the case that one works for some people while the other does not? Does Adderall do something else to those neurotransmitters that isn’t outlined in the articles I read? Obviously they have their own chemical structures, so what role does that play in the difference? Is relative dosage drastically different? Are there multiple ways to prevent the reuptake of a neurotransmitter?

I’ve taken both drugs, so my questions are definitely influenced by my experience as well, but I feel like the difference in effect is pretty widely accepted. I’m honestly just very intrigued!

Of course, if anything I wrote above is incorrect, please let me know and I will edit and notate asap. Appreciate any insight you might have!

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πŸ“°︎ r/AskPsychiatry
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πŸ‘€︎ u/mrwhoeverr
πŸ“…︎ Jan 07
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Is there a neurotransmitters for dummies type book?

Hi /r/Nootropics,

I have several mental health diagnoses (ADHD, anxiety, depression) and am looking for an approachable textbook (for patients) to explain how the brain, and specifically neurotransmitters work.

What does each neurotransmitter do? What kind of problems are associated with deficiencies and excesses in each, etc.

Is there anything out there that fits the bill?

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πŸ“°︎ r/Nootropics
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πŸ‘€︎ u/dave_613
πŸ“…︎ Dec 26 2020
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What neurotransmitters do Saffron target?

Some say Serotonin, some say dopamine. Anyone know?

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πŸ“°︎ r/Supplements
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πŸ‘€︎ u/curiousnootropics
πŸ“…︎ Dec 18 2020
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Anhedonia, Neurotransmitters, and You

Anhedonia

β€œTHE DISEASE WAS LIFE ITSELF … You realize all this ... when you look at the black hole and it's wearing your face.” - David Foster Wallace

First of all, if you’re reading this, I feel for you. And not in the sympathetic, β€œeverything’s gonna be ok” kind of cliches that our culture parrots to avoid answering tough existential questions. Total anhedonia is one of the worst things a human being can possibly experience, and I wouldn’t wish it on my worst enemy. If you’ve ever truly experienced this, I’m sure you’ll know where I’m coming from. When left unchecked, anhedonic depression quickly becomes a terminal illness. In writing this post, I sought to gather as much information as possible from my own experience and the scientific knowledge available to find some hope of recovery, or at the very least, some answers.

Doing this research was both enlightening and terrifying for me. It may be the negativity bias of people who post their anecdotal experience on the internet (fully recovered cases have less of an incentive to post?), but if anything knowing about the mechanisms of every antidepressant available and how, for some people, none of them will help, is quite disheartening. It seems to me that time is the number one factor in healing from most depression and is a likely confounding variable behind the success rates of medications.

Depression as it relates to anhedonia, as far as I conceptualize it, can fall into either one of these categories, or somewhere in-between.

(1 - Exogenous) Cases that are produced by external environmental factors / easily fixable lifestyle problems will often resolve permanently *with or without medication* when the person takes necessary steps to change. Medication like SSRIs in these cases can offset anxiety and reduce some symptoms like guilt / rumination until the episode passes naturally, but don’t help with anhedonia.

(2 - Endogenous) Cases where anhedonia is the core symptom are often chronic sufferers of depression, where medications like SSRIs can help to reduce some symptoms and prevent suicide, but don’t fix the core problem of anhedonia. If anything has become clear to me through this research, it’s that anhedonia is the single symptom that modern treatments have no consistency in treating.

My hope for myself is that my case is more like the first than the second, although I often struggle to believe that. A big point of confusion for me throughout this whole experience has been the fact that

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Is there a way to reset all neurotransmitters ?
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