Hi, sorry not to bring up any scary memories for anyone of you, I was curious what your experience was, if you felt the low and couldn't treat it in time or if it happened so suddenly. I ask because I've started a new job where I'll be moving a lot and active. My boss noticed my insulin pump the other day and asked if there was anything they need to know to do incase something happens. So I typed out what the symptoms of a low blood sugar are and how I can treat it what what they can do if I pass out or am to out of it to communicate or eat or drink. I have easy steps for them to follow like testing my blood sugar with a meter, using the glucagon kit, and even how to suspend insulin delivery on my pump. I'm also leaving a glucagon kit for them to have in the office and also where they can find it in my backpack if they can't find it there.
I've done my best to make this thing idiot proof because to me it's clear as day what to look for and what to do but I understand someone with no idea or experience of this could be lost.
I'm 99% sure this will never need to be used but it's to have incase and for everyone peace of mind, especially mine. I've never passed from a low or been so bad that I couldn't communicate but I'm only coming up on 2 years since diagnosis so I don't really know if some freak thing could happen or if it could all happen so fast you don't have time to notice. Again I'm 99% sure this thing will be expired and collecting dust before it needs to be used but I was curious about other's advice or their experience with this type of situation. Thanks:)
FA says Insulin is Beta 2, but it also says Glucagon stimulates glycogenolysis. what gives?
I've been a diabetic for almost 30 years and never needed it, fortunately. But I got curious after talking with someone who had to twice and have sequels for having the related severe hypoglycemias.
I’m all set for my test tomorrow.
After 10 years I finally had a low that required my Glucagon kit. I'm very lucky my girlfriend was able to give it to me at 2 AM, and grateful for my dog for waking her up. Has any one else had to use theirs? what was your experience like in the days after?
This happened a week ago, and since then all my markers have been off. My insulin sensitivity is increased, and I go low almost every morning before breakfast. I've had to adjust my basal rates, as well as my bolus ratios, and it seems to change through out the day.
I plan on speaking with my endo when I get an appointment next week, but I'm just curious if anyone has seen or heard of anything like this? Thanks! (also, getting jammed several times in the leg kinda sucks. 0/10 would not recommend).
I'll need to disconnect from my pump for over an hour AND dose some glucagon to "quiet the bowels" for an MRI. And no CGM.... A bit daunting for someone who likes tight control.
Anyone do this before? I'm thinking of taking a small dose of R but man I don't have a clue what the glucagon is going to do to my levels.
Any insights are appreciated.
Please discuss in the comments. Sorry if something like this has been done before, I was curious because I just had my first one yesterday. I was hiking with my family and forgot to bring low snacks. My dad, brother, and sister ran back to the car to find some carbs for me to eat and my mom stayed with me but I was getting worryingly low and my mom gave it to me. It hurts now lol.
I know it'll be different for different people, but does anyone have an approximation?
I have always been confused on the exact roles of these hormones in relation to each other. I know the following:
Insulin- promotes glucose uptake in the form of glycogen and lipids. It also promotes glycolysis to do even more to remove glucose from blood.
Glucagon- promotes glycogen and lipid breakdown. It also promotes gluconeogenesis to put more glucose in blood.
What I’ve read have always pitted insulin and glucagon as opposites. I can see in some cases that they are. However, isn’t (one of) the purpose of putting more glucose into the blood is so that the body can use it for glycolysis and make ATP when it needs energy (ex, fasting state)? Is this notion wrong, and if not, wouldn’t insulin and glucagon be promoting the same thing, just at different steps?
Morita Y, Ohno H, Kobuke K, Oki K, Yoneda M. Variation in plasma glucagon levels according to obesity status in Japanese Americans with normal glucose tolerance [published online ahead of print, 2020 Sep 10]. Endocr J. 2020;10.1507/endocrj.EJ20-0366. doi:10.1507/endocrj.EJ20-0366
Japanese Americans living in the United States are genetically identical to Japanese people, but have undergone a rapid and intense westernization of their lifestyle. This study investigated variability in glucagon secretion after glucose loading among Japanese Americans with normal glucose tolerance (NGT) according to obesity status. The 75-g oral glucose tolerance test (OGTT) was performed for 138 Japanese Americans (aged 40-75 years) living in Los Angeles. Plasma glucagon levels measured using the sandwich enzyme-linked immunosorbent assay were compared according to body mass index (BMI) categories among 119 individuals with NGT. The individuals were classified into three categories according to their BMI values: <22 kg/m2 (n = 37), 22-24.9 kg/m2 (n = 46), and ≥25 kg/m2 (n = 36). Fasting plasma glucagon levels and glucagon-area under the curve levels during the OGTT were the highest in the BMI ≥25 kg/m2 group. Fasting glucagon levels were correlated with BMI (r = 0.399, p < 0.001), fasting insulin levels (r = 0.275, p = 0.003) and the homeostasis model assessment-insulin resistance (r = 0.262, p = 0.004). In conclusion, our findings suggest that fasting hyperglucagonemia is associated with obesity and insulin resistance even during the NGT stage in the Japanese American population.
Post got removed from /r/fitness so posting here. Lots of emerging research about timing insulin spikes post-workout to route energy to be stored in muscle tissue over fat tissue but what about intentionally stimulating glucagon pre-workout to retrieve energy from fat tissue?
My glucagon is expired. It hasn’t been mixed yet. Have others used expired?
Also, having never used glucagon, I’m wondering what to expect blood sugar wise. Is it a one time spike or will I be high for a duration of time?
I’m going to be backcountry camping in a place with the threat of bears. I won’t be able to keep a snack with me in the tent for lows at night. In a worst case scenario, I’m curious if anyone has any experience with using a small dose of glucagon to treat a normal low and raise blood sugar to a manageable level (perhaps equivalent to eating 15g carbs)?