If you've ever passed out from low blood sugar or had to use a glucagon kit, what was your experience?

Hi, sorry not to bring up any scary memories for anyone of you, I was curious what your experience was, if you felt the low and couldn't treat it in time or if it happened so suddenly. I ask because I've started a new job where I'll be moving a lot and active. My boss noticed my insulin pump the other day and asked if there was anything they need to know to do incase something happens. So I typed out what the symptoms of a low blood sugar are and how I can treat it what what they can do if I pass out or am to out of it to communicate or eat or drink. I have easy steps for them to follow like testing my blood sugar with a meter, using the glucagon kit, and even how to suspend insulin delivery on my pump. I'm also leaving a glucagon kit for them to have in the office and also where they can find it in my backpack if they can't find it there.

I've done my best to make this thing idiot proof because to me it's clear as day what to look for and what to do but I understand someone with no idea or experience of this could be lost.

I'm 99% sure this will never need to be used but it's to have incase and for everyone peace of mind, especially mine. I've never passed from a low or been so bad that I couldn't communicate but I'm only coming up on 2 years since diagnosis so I don't really know if some freak thing could happen or if it could all happen so fast you don't have time to notice. Again I'm 99% sure this thing will be expired and collecting dust before it needs to be used but I was curious about other's advice or their experience with this type of situation. Thanks:)

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πŸ‘€︎ u/t1birdie
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Does the Beta-2 receptor promote both Insulin AND Glucagon secretion?

FA says Insulin is Beta 2, but it also says Glucagon stimulates glycogenolysis. what gives?

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πŸ‘€︎ u/PunMuffin909
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Advice needed please! Is there somewhere I could donate glucagon that is past expiration but potentially still good? I don’t want it to go to waste πŸ₯²
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πŸ‘€︎ u/kikithegirl
πŸ“…︎ Jan 30
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People who used Glucagon, can you tell about your experiences?

I've been a diabetic for almost 30 years and never needed it, fortunately. But I got curious after talking with someone who had to twice and have sequels for having the related severe hypoglycemias.

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πŸ‘€︎ u/VladTepesDraculea
πŸ“…︎ Dec 20 2020
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Glycogen vs glucose vs glucagon vs glycerol

I’m all set for my test tomorrow.

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πŸ“…︎ Dec 10 2020
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EMA backs Xeris' ready-to-use glucagon for approval, setting up showdown with Novo and Lilly fiercepharma.com/drug-del…
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πŸ‘€︎ u/gravballe
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In my philosophical moments of hypo I was wondering if there is any pump that automatically injects glucagon if your Cgm detects a hypo, do you know any?
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πŸ‘€︎ u/FajardoND
πŸ“…︎ Dec 16 2020
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Finally got my new glucagon in the mail today πŸ˜† It’s better to think that people will use this on me (god forbid) since so many people are scared of needles
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πŸ“…︎ Aug 21 2020
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Xeris Pharmaceuticals Receives Positive CHMP Opinion for Ogluoβ„’, Its Ready-To-Use (RTU) Glucagon for Injection, for the Treatment of Severe Hypoglycaemia in Adults, Adolescents, and Children Aged 2 Years and Over With Diabetes Mellitus finance.yahoo.com/news/xe…
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πŸ‘€︎ u/gravballe
πŸ“…︎ Dec 11 2020
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EMA backs Xeris' ready-to-use glucagon for approval, setting up showdown with Novo and Lilly fiercepharma.com/drug-del…
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πŸ‘€︎ u/gravballe
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when I study for 3 months and still have to google what insulin and glucagon do
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πŸ‘€︎ u/ventibetch
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The Role of Insulin/glucagon Ratio and Cell Redox State in the Hyperglycemia Induced by Exposure to Pulsed Electromagnetic Fields in Rats researchsquare.com/articl…
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πŸ‘€︎ u/modernmystic369
πŸ“…︎ Dec 30 2020
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I had to use my Glucagon kit, now everything has changed

After 10 years I finally had a low that required my Glucagon kit. I'm very lucky my girlfriend was able to give it to me at 2 AM, and grateful for my dog for waking her up. Has any one else had to use theirs? what was your experience like in the days after?

This happened a week ago, and since then all my markers have been off. My insulin sensitivity is increased, and I go low almost every morning before breakfast. I've had to adjust my basal rates, as well as my bolus ratios, and it seems to change through out the day.

I plan on speaking with my endo when I get an appointment next week, but I'm just curious if anyone has seen or heard of anything like this? Thanks! (also, getting jammed several times in the leg kinda sucks. 0/10 would not recommend).

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πŸ‘€︎ u/JollyWaffleman
πŸ“…︎ Aug 16 2020
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40 years later, I finally got an updated Glucagon Kit for Emergencies, the Gvoke HypoPen. Insurance wouldn’t let me have the nasal spray but this looks easy enough to use.
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πŸ‘€︎ u/readeym
πŸ“…︎ Oct 03 2020
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Glucagon for MRI???

I'll need to disconnect from my pump for over an hour AND dose some glucagon to "quiet the bowels" for an MRI. And no CGM.... A bit daunting for someone who likes tight control.

Anyone do this before? I'm thinking of taking a small dose of R but man I don't have a clue what the glucagon is going to do to my levels.

Any insights are appreciated.

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πŸ‘€︎ u/maldonco
πŸ“…︎ Sep 12 2020
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Have you ever had to take a glucagon shot?

Please discuss in the comments. Sorry if something like this has been done before, I was curious because I just had my first one yesterday. I was hiking with my family and forgot to bring low snacks. My dad, brother, and sister ran back to the car to find some carbs for me to eat and my mom stayed with me but I was getting worryingly low and my mom gave it to me. It hurts now lol.

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πŸ“°︎ r/diabetes_t1
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πŸ‘€︎ u/AllyATK
πŸ“…︎ Sep 21 2020
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Xeris Pharmaceuticals Receives Positive CHMP Opinion for Ogluoβ„’, Its Ready-To-Use (RTU) Glucagon for Injection, for the Treatment of Severe Hypoglycaemia in Adults, Adolescents, and Children Aged 2 Years and Over With Diabetes Mellitus finance.yahoo.com/news/xe…
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πŸ‘€︎ u/gravballe
πŸ“…︎ Dec 11 2020
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Because My Insurance Would Not Cover the Glucagon Kit or Baqsimi, I called Lilly to see what my options were. They have a program that allows those who don't have insurance, of an insurance company that doesn't cover the drug, go buy it out of pocket for an extremely low price. $1.75 for me!
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πŸ‘€︎ u/SenileTomato
πŸ“…︎ Jul 02 2020
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How much does a glucagon shot increase your blood sugar, and how long does it take to do so?

I know it'll be different for different people, but does anyone have an approximation?

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πŸ‘€︎ u/zaureau15
πŸ“…︎ Aug 10 2020
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Honestly one of the scariest nights of my life. Glucagon and 10 juice boxes and pump disconnected for 3 hours later I was able to stay above 80
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πŸ‘€︎ u/TxSchatt
πŸ“…︎ Jul 09 2020
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GLUCAGON increases insulin release?! Came across this flash card on uWorld. Can someone please help me out with this?
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πŸ‘€︎ u/Dawgtor101
πŸ“…︎ Aug 12 2020
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Insulin vs Glucagon

I have always been confused on the exact roles of these hormones in relation to each other. I know the following:

Insulin- promotes glucose uptake in the form of glycogen and lipids. It also promotes glycolysis to do even more to remove glucose from blood.

Glucagon- promotes glycogen and lipid breakdown. It also promotes gluconeogenesis to put more glucose in blood.

What I’ve read have always pitted insulin and glucagon as opposites. I can see in some cases that they are. However, isn’t (one of) the purpose of putting more glucose into the blood is so that the body can use it for glycolysis and make ATP when it needs energy (ex, fasting state)? Is this notion wrong, and if not, wouldn’t insulin and glucagon be promoting the same thing, just at different steps?

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πŸ‘€︎ u/correctglass
πŸ“…︎ Aug 27 2020
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Variation in plasma glucagon levels according to obesity status in Japanese Americans with normal glucose tolerance - Sep 2020

Morita Y, Ohno H, Kobuke K, Oki K, Yoneda M. Variation in plasma glucagon levels according to obesity status in Japanese Americans with normal glucose tolerance [published online ahead of print, 2020 Sep 10]. Endocr J. 2020;10.1507/endocrj.EJ20-0366. doi:10.1507/endocrj.EJ20-0366

https://doi.org/10.1507/endocrj.ej20-0366

Abstract

Japanese Americans living in the United States are genetically identical to Japanese people, but have undergone a rapid and intense westernization of their lifestyle. This study investigated variability in glucagon secretion after glucose loading among Japanese Americans with normal glucose tolerance (NGT) according to obesity status. The 75-g oral glucose tolerance test (OGTT) was performed for 138 Japanese Americans (aged 40-75 years) living in Los Angeles. Plasma glucagon levels measured using the sandwich enzyme-linked immunosorbent assay were compared according to body mass index (BMI) categories among 119 individuals with NGT. The individuals were classified into three categories according to their BMI values: <22 kg/m2 (n = 37), 22-24.9 kg/m2 (n = 46), and β‰₯25 kg/m2 (n = 36). Fasting plasma glucagon levels and glucagon-area under the curve levels during the OGTT were the highest in the BMI β‰₯25 kg/m2 group. Fasting glucagon levels were correlated with BMI (r = 0.399, p < 0.001), fasting insulin levels (r = 0.275, p = 0.003) and the homeostasis model assessment-insulin resistance (r = 0.262, p = 0.004). In conclusion, our findings suggest that fasting hyperglucagonemia is associated with obesity and insulin resistance even during the NGT stage in the Japanese American population.

https://www.jstage.jst.go.jp/article/endocrj/advpub/0/advpub_EJ20-0366/_pdf

https://preview.redd.it/4kh9lojjxhm51.png?width=2057&format=png&auto=webp&s=16e70715335e284d97a3aad33b866ce20efe9617

https://preview.redd.it/5ckktwsnxhm51.png?width=1766&format=png&auto=webp&s=9bb1e9d4c2922485822cc00371356d71037415b4

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Alleviation of Depression by Glucagon-Like Peptide 1 Through the Regulation of Neuroinflammation, Neurotransmitters, Neurogenesis, and Synaptic Function frontiersin.org/articles/…
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Cacao polyphenols regulate the circadian clock gene expression and through glucagon-like peptide-1 secretion (2020) pubmed.ncbi.nlm.nih.gov/3…
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πŸ“…︎ Aug 22 2020
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Baqsimi (glucagon) Anyone in Canada πŸ‡¨πŸ‡¦ know of a coupon to make it cheaper somehow?
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πŸ‘€︎ u/n0w0rnever97
πŸ“…︎ May 27 2020
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Can somebody point me to more information on the role of glucagon in fitness and weight loss? We know a lot about insulin and its role as an energy storage hormone but seemingly little about the energy removal hormone glucagon

Post got removed from /r/fitness so posting here. Lots of emerging research about timing insulin spikes post-workout to route energy to be stored in muscle tissue over fat tissue but what about intentionally stimulating glucagon pre-workout to retrieve energy from fat tissue?

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πŸ“°︎ r/endocrinology
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πŸ‘€︎ u/heyhodadio
πŸ“…︎ Aug 03 2020
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So I’m teaching My girlfriend how to use Glucagon. This is the instructions. Imagine being in an emergency situation without any idea what to do and you whip this out. the essence is only like two super basic steps but it's completely buried. This is not functional.
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πŸ‘€︎ u/coreyb96
πŸ“…︎ Apr 18 2020
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Has anyone ever used expired glucagon?

My glucagon is expired. It hasn’t been mixed yet. Have others used expired?

Also, having never used glucagon, I’m wondering what to expect blood sugar wise. Is it a one time spike or will I be high for a duration of time?

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πŸ“°︎ r/diabetes_t1
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πŸ‘€︎ u/Wuke-Skywakuh
πŸ“…︎ Jun 01 2020
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Micodosing glucagon: options?

I’m going to be backcountry camping in a place with the threat of bears. I won’t be able to keep a snack with me in the tent for lows at night. In a worst case scenario, I’m curious if anyone has any experience with using a small dose of glucagon to treat a normal low and raise blood sugar to a manageable level (perhaps equivalent to eating 15g carbs)?

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πŸ“°︎ r/diabetes_t1
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πŸ‘€︎ u/diabeticdiva
πŸ“…︎ Jul 01 2020
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Glucagon

Has anyone ever had to use the emergency glucagon?

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πŸ‘€︎ u/Mary_June
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