Parental gametes have unique methylation patterns. Early on in embryonic development, there is a demethylation cascade that largely resets the methylome. Obviously imprinted, sex-dependent methylations are predictably reestablished in the embryo, but I’m curious how much of the unique, non-imprinted methylation patterns from the parental methylomes make it through to the embryo.
The rhino Cryovault is a biobank that holds the largest genetic repositories of rhino DNA, gametes, and tissues in the world; frozen and preserved indefinitely. What does it mean to save a species? What happens if, in the absolute worst-case scenario, we fail? While Hemmersbach Rhino Force is doing everything in their power to make sure that does not happen, they do have one last ace – the rhino Cryovault.
Like half of haploid gametes that can fuse into haploid gametes
Currently in the process of beginning my transition with GenderGP while I wait to actually get somewhere on the NHS waiting list. Requested the blood tests specified by the GenderGP doctor I spoke to, and also requested a referral for gamete storage.
They refused me for the first one saying that they "don't have the expertise for it" and that I should go through the NHS route (which I already am lol). this reasoning seems kinda sus to me but that's besides the point I guess. For gamete storage, they said I'd need to request a referral for it from GenderGP, for some reason. When I got in contact with GenderGP about it though, they linked me to their fertility consideration page, and that I could "either ask local hospitals or other local private services if they will be willing to do the blood tests" or order one of their blood test kits.
Needless to say, I'm a bit confused and lost on what to do now. What should be my next step?
(Note: I live in Wales)
so, I recently watched Alien Worlds, and while I generally did not like it, there was one thing that interested me; the Grazers had worm-things that allowed them to breed; my challenge is this:
There is the common theme that gametes do not need moral consideration because of their lack of a full set of 2n, 46 chromosomes.
But Down's Syndrome people are still human and they have 47 chromosomes.
Chimera's have 92 chromosomes and they are still human.
Clearly, if you give moral consideration to DS & chimeras, it isn't number of chromosomes that determines your moral worth. Yet the idea that a zygote has 46 chromosomes seems to be enough to be considered of the same moral value.
So why, then, are you (rightfully & as you should) giving moral consideration to DS and chimeras?
Why, then, are you not giving moral consideration to gametes?
It seems as if there is something else going into this moral consideration.
Thoust is a tboi steam mod called the binding of synth which basically replaces all the music with synthwave (basically vapourwave) and considering yubs channel is surrounded in vapourwave esthetic (was) i was wondering what if yub saw this, commented it, suprise suprise woah he didnt so if you wanna hear vapour wave while he does more pc tboi vids then help a gamer out and the second largest channel on youtube, thank you for coming to my ted talk
I was wondering can astartes still produce the genetic material needed to produce a child. Let's say Guilleman Tugs on cawl's leash to find out who sends a Biologician to harvest samples from healthy adult astartes said techpriestess Manages to harvest the samples utilizing a method similar to how they extract semen from bulls before implanting said samples into harvested eggs. Would the child from this experiment be a healthy human
Hello. So, I am a woman in my early 20s dealing with infertility due to a genetic condition. Specifically, I have primary ovarian failure, which means that I have no eggs in my ovaries. I have been considering familial gamete donation with eggs possibly donated from one of my two sisters (this would be way in the future btw). I was just wondering if any adoptees could provide their perspective on the ethics of this? I’ve seen that adoption tends to be viewed as a trauma due to separation from the biological parent, and I don’t want to willingly inflict trauma on an infant. Is it the same with gamete donation, since you aren’t the resulting child’s biological parent?
My journey to accessing fertility preservation was an absolute nightmare. This is due to primarily Covid, but also funding issues. I am writing this post in the hope it greatly simplifies navigating the process for others, so they don't have to go through what I had to.
My journey began in January when I finally received my diagnosis from a specialist, went to visit my GP and asked for NHS-funded fertility preservation. My GP (like many GP's) was unsure how to do this and advised they'd investigate and get back to me. It became apparent that they forgot to do this. I saw another GP 4 weeks later, who advised the process and put in a funding application. There were unfortunately admin issues that meant I didn't receive my approved funding until another 6 weeks later. By this point it was too late, as all non-emergency/ imminently life-threatening procedures across the entire NHS were basically postponed because of Covid-19 to allow there to be more hospital beds, and minimise transmission between healthcare workers.
I got there eventually. In July I was finally advised the fertility clinic could see me. However, that same clinic went into a second lockdown meaning my treatment was postponed until late August, and I returned for a second appointment this month.
I've now finally started hormones 10 days ago - whoop! :) NHS funded fertility preservation during these strange times we find ourselves in definitely is possible. I'd definitely advise however, if when reading this post your region is about to enter another Covid lockdown, you act quickly, forget NHS funding (if possible), and find a means of self-funding to avoid going through the turmoil of waiting (and not knowing when the wait will be over.)
If however another lockdown in your region seems unlikely at the time of reading this post, then this is how you can pursue NHS funding.
I won't go into all the in's and out's. Just here's what you need to do:
Tip: if you live in London you most likely belong to the North West London Consortium (Group) of CCG's. The 8 London CCG's (Brent, Harrow, Hillingdon, Central London, West London, Hammersmith & Fulham, Hounslow and Ealing) all abide by North West London Consortium of CCG's funding policies
This post is for the Wiki. If you have an answer to contribute for this topic, please do. Please stick to answers based on facts and your own experiences.
This post is meant to be a resource for sourcing donor gametes (eggs and sperm) and donor embryos. Please post content and links to:
If you are looking for information on the donor process including timeline, medical, or emotional aspects; please refer to our previous posts:
Donor Eggs - https://www.reddit.com/r/infertility/comments/j38lxu/faqs_donor_eggs/
Donor Sperm - https://www.reddit.com/r/infertility/comments/iyxwj8/faq_tell_me_about_donor_sperm/
There will be a Donor Embryo general post at a later date (link will be added).
Thank you for contributing!
Additional resources may be available at these subs:
Had confimation today that my fertility/endo team will be going ahead and applying for funding on my behalf for my egg harvesting operation, I've been waiting for 2 years for this specifically so this is great news.. he sounded confident that I would be accepted, but I cant help think I need to prepare myself mentally and financially as much as I can just incase it falls through and I'm not accepted funding too.. has anyone got experience in this, and could maybe explain more how getting funding through NHS for this works, he asked what area of Birmingham I live in.. does this make a difference? A bit of background I'm 26 and trans ftm.. I have Endometriosis stage 4, undiagnosed for 10years so its quite a mess inside there (my FSH blood test was worryingly high in his opinion, but then my AMH came back ok- he's still concerned about those two results being so different) and Crohns disease (have had 4 bowel resections in past) both impact my daily life a lot and so its important I have the eggs harvested before starting HRT testosterone which should hopefully help control the Endometriosis.
Thanks in advance people I'd really appreciate any insight at all!
Just wondering if anyone who has had gamete storage/egg harvesting done could explain roughly what the process is like.. I'm aware of the general procedure itself and know you have to self inject medication daily (150units gonadotropin) for 2 weeks to expand the eggs.. does that affect you in any major ways apart from the obvious? Is there visible/uncomfortable bloating/swelling? I have Endometriosis stage 4 and Crohns, so I'm expecting it will definitely be more painful than the average persons. Also emotionally did you find the medications had any influences? I'm at college atm and I'm wondering if I'll be fine to continue going there daily or of it would be best to book the 2 weeks off if theres going to be any uncomfortable times.. if anyone could shed any light I'd really appreciate it.
Thanks a lottt
I’m a third year zoology student currently studying an evolutionary biology module. My lecturer briefly mentioned this in a recent lecture on sexual selection. She said that there hasn’t been much research done on it and we still don’t understand why it occurs.
Does anyone have any extra insight into this?