I'm soon to be trained on how to administer avonex, I don't drink alcohol that often nor do I have any desire to on a average day,
However I do enjoy drinking at festivals and gigs, I've seen on google that it can increase liver issues with avonex, I was just wondering what everyones experiences and thoughts on this are,
Hello community! I was diagnosed in March of this year and started Avonex immediately. There was so much information at the time that I'm not sure I did proper research, because it was just a lot to take in at the time.
Avonex has been going great, I have virtually no side effects. However, I've been reading it's not as effective as other treatments. I'm looking at Ocrevus as an option. I'm wondering if I should bring this up at my 6 month follow up.
My question is this: Being that we are in a global pandemic, should I wait to switch to Ocrevus? From what I understand you would be immunocompromised more so than Avonex? Is that true? TIA for your advice.
I had my first infusion of Rituximab on Friday. Other than some minor flushing, I had no problems! I wish that I switched from Avonex earlier!
I've been on Avonex for 9 years and now my asshole insurance suddenly wont pay for it anymore. I'm going to talk to my doctor this Monday about switching to Tecfidera. How has everyone's experience been with it?
Hello - I was diagnosed in March of this year and started weekly Avonex injections. I'm one of the lucky ones that has zero side effects from Avonex. However, I keep hearing about these twice a year infusions with Ocrevus. I'm wondering if you guys can tell me your experience with Ocrevus, and if you are worried and PML. How do you feel? Does most insurance cover well (USA)? How long is the fusion, etc. Thank you!
I had my first injection of Avonex on Saturday. It was 1/4 dose to start with. I had zero side effects. Is this because it was 1/4 dose or did I just get lucky? Next week will be 1/2 dose.
Took my second titrated dose of avonex this morning and I feel awful. I just want to sleep, but I am so sore and my body aches and I can't get comfortable. Also I have no idea what may or may not interact with avonex to take so I can rest. What works for you?
This sub has been awesome, thanks in advance!
Wondering if there are people with MS who are/have been treated with Avonex who now suffer with chronic ITP?
I just wanted to post this in case anyone else taking Avonex is suffering as much as I have been.
Thanks to /u/daelite, and trying not to sound hyperbolic, I read their comment reply here in this post
After reading that and getting their reply in the following comments, I began researching to prepare something more than "I read it on the internet" to discuss with my neurologist in the morning (and, quite frankly, write it down in a calendar reminder so I wouldn't forget if I got to sleep tonight...).
Instead of finding a couple of blogs with others like /u/daelite used to, I instead found countless research studies showing that Avonex has been the cause of the destruction of my life due to depression for nearly a decade, and that not only is this apparently well known within the general scientific community for MS patients, but also known, studied, and published in countless medical journals for the last decade by the governments of multiple countries as well (ok sorry, "decade" is an exaggeration, it's been known since 2012).
I complained more about why so many neurologists have allowed me to suffer and think it's entirely my fault I'm depressed by telling me I need to "find a better therapist", or "try this new depression medication", or "you need to try exercising more frequently" because "maybe not exercising enough is preventing the depression medications from working for you".
FYI: I have been doing physical therapy for 2-3 hours/day, 3 times per week, since the year prior to my diagnosis - plus, because of the guilt of feeling like the depression is my own fault, I have also been doing additional at home exercises of the physical therapy exercises they've given me six times a day on the days I don't have therapy, and four times a day on the days I do have therapy... All of which just causes me further fatigue and prevents me from being able to do ANYTHING on ANY DAYS because all I'm doing is trying desperately to get rid of my depression by pushing myself as hard as possible with exercise because I've spent a decade believing all of this is entirely my fault.
I'm SO tired, I'm missing out on my entire life, I'm unable to stop crying again, and I'm still feeling SO defeated.
I'm sorry for the horrific grammar and probably the worst run-on sentences ever written in the English language, but I'm just done.
Please [check out the rest of the references](https://ww... keep reading on reddit ➡
I just started on it and I've done 3 shots so far. I do them on Thursday and I've noticed that on Friday any numbness I already had is noticably worse and I can hardly move my legs, have horrible muscle spasms in the middle of the night, headache in the same spot every time and I'm completely fuckin drained. Will this go away once my body is more used to the medicine?
Hi y'all. I've been on Avonex for ~15 months. Over the last few months, I've noticed that my hair is thinning. Now... I am a 45 year old, and I know that some 45 year olds gents have thinning hair. That's fine. That may be the case, but I've seen articles that Avonex is associated with hair loss in a small % of cases.
Anyone on this sub have this issue while on Avonex?
Certainly I'll bring it up with Neuro when I see him next. But if anyone has experienced this, let's chat a bit!
I'm shivering, legs hurt and my head is weird noises when I move it. And no energy. The fun day has started.
Hi there r/multiplesclerosis!
I have a question about fasting on MS.
I’m currently on 15mg daily dose of Prednisolone and I’m working my way up to a full dosage of Avonex. Tonight, as my 5th injection, I’m taking 3/4 syringe.
I’m living in Tokyo and we’re currently experiencing a heatwave (highest daily temperature will be over 90 for the next week). I’ve always been chubby, but the heat is unbearable, and I don’t want to risk another relapse due to heat. So I’m thinking about going on a 3-5 day fast to jump start a diet so I’m less affected by the heat. It’s gonna be another 4-6 weeks of intense heat...
I have fasted for up to 10 days before my diagnosis, and I have done six or seven 3-to-5-day fasts in the past to use as a break from bad eating/drinking habits. I have always felt pretty good afterwards and I know how to fast safely and responsibly.
What are your experiences with fasting if you have any? Would you say intermittent fasting is better?
Last night my partner gave me my weekly Avonex injection (we use the 1.25 inch prefilled syringes, intramuscular injection into the top of my thigh). As he pulled the needle out, he told me that blood shot out about an inch high from the injection site. I never watch him inject (afraid of needles, which is why he injects me) so I didn't see the apparent mini geyser action but when I looked at my leg it immediately bruised up like crazy. I watched the bruise appear and expand like within one second of the injection.
Had anyone ever had this happen before? Did we hit something like a vein? My other concern is that the medication came flying back out with the blood...does anyone know anything about that? I tried to call the MS Alliance but they're closed on weekends.
Any info would be great! Oh also for background, I just started Avonex, my first DMD and I'm on my 9th injection.
Went and met with my neurologist yesterday and we discussed Copaxone and Avonex. I know every person is different and every body reacts differently, but am looking for some feedback on what your experiences (good or bad) were with either one. I have a bit of a needle phobia that I am going to have to work on and will get over after some time. Any information is appreciated! :)
So they called my wife today and said that she needs to take either rebif or copaxone. any information would be AMAZING. Thanks everyone, you are always a huge help.
earlier tonight, the avonex pen i was supposed to use decided to poop, and now since im away from home, i cant properly get my injection until monday. currently a little worried, despite what i'd heard from the nurse. am i right to be concerned, or is it no big deal, and im getting stressed out for nothing?
My neurologist asked me to look at Copaxone and Avonex as treatment options. Due to a history of depression/anxiety, I am leaning towards Copaxone. However, I've noticed that 'anxiety' seems to be a common side-effect of it, which is also no bueno. However I'm also worried about the flu-like symptoms of Avonex as I'm getting to the gym daily to help with my mood issues, and I don't want to give myself an excuse not to go. But then I saw that Copaxone can have flu-like effects as well.
So, my questions for you experienced people:
If you've been on Avonex despite having a history with depression, what effect did the drug have on your mood?
If you've been on Copaxone, did you experience an increase in anxiety? If so, was this mostly an immediate post-injection effect, or did it consistent raise your anxiety levels across the board?
For users of either drug, did you eventually stop feeling the side-effects as much, or are they something that I'll have to live with as long as I am taking the drug?
I'll also talk to my neuro about it, but I wanted to crowd-source some experience as well.
Ciao a tutti.. prima o poi racconterò anche la mia storia.. ma per ora sarei curioso di sapere se sono solo io a riscontrare problemi circa l’auto somministrazione di Avonex per conclamata presenza di penne difettose o se anche altri hanno avuto questo “piacere”
whats the difference between these 2 meds, other than the frequency of injections?
I've been traveling in Europe with 2 weeks left (two doses). I brought enough medication with me for the whole trip but I lost part of my luggage which has my meds. Should I just get two from a pharmacy? Would a pharmacy even have this medication? Would travel insurance cover this? Or should I just skip these two doses and return on them when I get home? Thank you for any info you might have.
I've been on Avonex for about a year now. I was diagnosed November 2015 and they immediately started me on the treatment. I take it every Wednesday (yay today is shot day) and I do all I can to make the flu like symptoms manageable, but I'd say it's about half and half manageable and absolutely miserable weeks. Like it feels like I'm dying throughout the night. I don't want to switch because I do like the once a week shots and my neuro believes this would be my best fit. Do I have any other fellow Avonex injectors here that can share their experience? Maybe I could ask him to prescribe me pain medication to manage when it gets worse? Will it ever stop feeling that way?
My other concern is the nurse mentioned moving around my injection sites so I don't get a cartilage build up. I'm starting to feel a small knot in my leg and I'm wondering if that's what it is. How long does it take for the cartilage to build even though I'm alternating legs and moving around the injection site?
My next check up and round of MRIs is in six weeks so any major concerns I have, I'll be sure to ask, I just need some advice and thoughts from others dealing with this shit. MS sucks, but I know it could always be worse and I'm just trying to stay positive.
My girlfriend has been dx with Ms about 3 months ago. She has been prescribed Avonex to be taken once every week. Understandably she is very sad the day she has to administer the injection. It's not the administration itself that gets her, as we have the pen version of the product, however the side effects that ensue are bad. She always takes it just before we go to bed and tries to manage the flu like symptoms by taking paracetamol before the injection and also after. In fact we set alarms during the night so that we wakes up and takes more paracetamol.
Although there has been an improvement, for example at the beginning she would experience severe chills (these have stopped), she still has bad flu like symptoms the day after characterised by general body pain, headache and extreme fatigue. To the point that more often than not she skips the day at work or works a few hours from home.
Is anyone here on Avonex? Do you experience the same thing? Any other side effect management strategies you can recommend? Are these symptoms enough to request a change in medication?
I was diagnosed RRMS in December '16 with my initial symptom presenting as Optic Neuritis in the previous July.
I took Avonex injections for approx 8 weeks before I decided to come off it as the side effects were initially unbearable - and although these became manageable by taking ibuprofen and rest the damage had already been done. I have quite severe anxiety and a couple of the injections left me slightly traumatised as I pushed too hard into the muscle and limped for days afterwards.
Anyway- MY QUESTION- does anyone not take preventive medications?
I am due to see my Neurologist and I know he will suggest Tecfidera but I feel like I don't have time for the side effects due to work commitments. I currently function extremely well and all of my day to day symptoms are manageable so I don't feel like I can handle the added strains of medication side effects. I currently manage without neuropathic painkillers having previously been on Amilitryptaline and Lyrica- which again couldn't be arsed with the drowsiness/hallucinations and other crappy side effects.
It's weighing on my mind as I'm aware preventative meds can reduce future relapses by upto 50% (statistic from MS nurse - haven't found source). Should I risk not being on meds to gain a relatively normal life right now in the present?
I do plan on bringing this up with my Neurologist to see what his opinion is.
Note: My older sister has PPMS and has never taken any preventative meds although she is on a massive cocktail of neuropathic painkillers. My dad had RRMS and has never taken any medication at all for this.
I understand giving medical advice isn't ideal in this situation but any input about your own personal experiences and how you made decisions regarding meds would be appreciated.
Hi all, and happy new year to you :-)
Has anyone else experienced chest pain? My gf woke me up at 4am the other morning with severe pain in her chest, saying it felt like a heart attack, or that someone was sitting on her chest?! I phoned for an ambulance and they asked me a few questions, then despatched an ambulance, but before it got to us she started feeling better so I cancelled it.
She started Avonex 2 weeks ago, and her second injection was 3 days before this chest pain. We phoned the manufacturer and they said it was unlikely to be linked to the Avonex, and her MS nurse agreed. My gf has her 3rd injection due tomorrow and is pretty nervous about it.
It's worth mentioning she was involved in a car crash a couple of weeks ago, in between her 1st and 2nd injection. She smashed her head and arm pretty bad, and the shock resulted in a flare up / relapse (not quite sure of the difference yet) making her leg go heavy. I wonder if this shock could have been a cause of the chest pain...
The good news is that she's experienced very few other side effects! As long as she's got paracetemol and ibuprofen in her system at the same time she seems ok. A bit drowsy and definitely not 100%, but it's more than manageable.... so far....
How are you guys getting on with Avonex? Have you ever had chest pain? Do you think it's related? Also, for those of you who have used Avonex for some time: Do the other side effects get better in time or can we expect the same for the foreseeable future?
Do you think the shock of the car crash was to blame?!
Ok, so I've been taking avonex once a week for over 4 years now. I'll spare how horrible it is because there are worse drugs out there. I normally drink once a week or so and never had any issues (never on the day of the injection, that feels like crap). I'm traveling next month for three weeks (music festivals) and been intending to indulge in ethanol. I didn't know that avonex is hard on the liver till now. I can't find any research or articles online on the subject, could anyone help shed light on the matter?
The US now has the Avonex pen and I just used it. Quick, easy and pretty much pain-free. :)
So I am posting on behalf of my wife. She was diagnosed in December of 2012. She was having episodes of losing vision in her eyes and the doctor put her on Avonex. She has been doing well and has only had one issue of losing her vision about 2 months ago. However, recently she became numb all over from the neck down. So I guess my question is, should we consider switching medicines or does Avonex take a little more time to take effect?
Has anyone had any experience with their interferon and hair loss? I have noticed it the past few months (I started Avonex in July 2013) and its getting really noticeable. From what I have read it is a common side effect. I was just wondering if anyone had experienced this and if it ever got better?
Hello all. I was diagnosed in May (three days after graduating college, hooray) and was first put on Avonex after steroid infusions, etc. Now I was completely fine with getting shots and other needle procedures but after Avonex, that's not the case anymore.
I guess it started when the nurse came in to train me on how to take it. She just flipped through the book for a little bit then told me to do it. I had never held a syringe before in my life and here she is, saying 'just do it', like it's no big deal. There was no practice, just my first injection. So that was rough, but after a little while, I managed to give myself the injection. Injection number 2: it took 30 mins to eventually stab myself, crying the whole time. Injection 3: sat in the bathroom for several hours, sobbing, and never managed to give myself the shot. The next day I went in to see my doc and he gave me the shot, but not after I screamed and sobbed for 30 mins (still wasn't happy it happened).
That's when my Neuro decided to put me on Gilenya. Yay! I am so much happier now.......... except that now I can't be around needles. I went to get a flu shot and had a panic attack and wound up not getting it. Another panic attack when I needed to get an injection of dye for an eye test (thanks to Gilenya). Even seeing it happen on TV or in a movie, I freak out and start crying a little.
Has anyone here gone through this? Any advice?
I have been taking Avonex for over a year with major symptoms of depression and the usual flu symptoms every week. My neurologist states that switching from Avonex to Ocrevus would be too risky due to PML risk and that the Avonex is keeping everything stable, pretty much to suck it up. Should I get a second opinion about switching?
While surfing online for information about IM injections I came across information that Biogen ‘s medicine Avonex is now offered in a new format –a pen.I’ve been using personal Avoject im injector but I would like to see how Avonex pen works. I’ve tried contacting Biogen but I still didn’t get answer. Would anyone be willing to help me get one used Avonex Pen Auto Injector and post it to me? I'll compensate you, of course.
Ok. 2016 kinda sucked for me. After 7 MRIs, tons of blood work, and a spinal tap, I was finally diagnosed with RRMS.
My first major symptom was blurry/painful vision in my right eye back in the early fall. Did the normal steroids (which are less than pleasant). Things got better a week or so later but lost some vision quality in the right eye.
A month later I can't feel my big toe...
More steroids. It went away...
Then in December, my neuro started me on Avonex. Got the expected flu-like symptoms. They last a day then go away. But... I noticed I was kind of "foggy". I went up to the next dose the following week and again the flu feelings. Then I felt even more foggy and almost dizzy. Things seemed to get worse from there. More dizziness...
I noticed I had double vision in my left eye's field of view. I called my neuro who was heading out on vacation for the holidays. He said its probably just the Avonex. Go call the drug company. I did, but all they could/would do was to read the same list of aide effects from their website and tell me to go talk to my neuro... Yay, runaround... Back and forth for 2 weeks.
So I did my homework. Nowhere in the FDA published data is double vision listed as a known or potential side effect of Avonex. Dizziness yes, but not double vision.
Fast forward 2 weeks. I was then on my 3rd increased dose of Avonex. At this point I can barely standup from the dizziness and I see double everything.
No response from my neuro over the holiday. A relative who's in the medical field said to "get my ass to the ER".
Lucky I did. After 8 hours and another MRI, the docs confirmed I was both A) having some kind of reaction to Avonex causing the dizziness and B) having another bout of optic neuritis, this time in my left eye.
Still recovering. I've stopped taking Avonex for almost a week and a half. Still dizzy but improving. Had more steroids and the double vision is improving too. I fear the back and forth with my neuro may have let the neuritis do more damage than if he was responsive to my concerns...
Anyhow, wondering if anyone else has had problems with Avonex.
How often do you have flare-ups? I feel like 3 issues in almost as many months seems high?
Anyone can recommend a good neuro/MS expert in the pacific northwest?
I'm a MS noob here. I'm gradually coming to terms with "I guess this is my life" but really worry for my wife as she has to watch all this happen.
I took Contac Cold & Flu to try to combat the flu symptoms and even did my injection earlier today at around 5pm. Maybe an hour or so later, I started feeling an ache in my back. That turned into every part of me aching, chills, headache and fever which got worse at 9pm. It's now 1:54am and I needed to try to sit up for a bit since I can't stay asleep.
I just took some more meds for the fever in hopes that it will go down and I could try to get more sleep. This has been the worst round of flu symptoms yet while on Avonex. Yikes.
Anyone have any advice or could maybe recommend something that actually works on fevers? :P When I feel this sick, my body doesn't let me sleep (and I'm supposed to go to Brimfield, MA for an antique show today which I reaaaally want to go to - they have some fantastic falafals - I kind of want to push myself to still go even on little sleep).
Thank you for taking the time to read this. :)
Edit: Thank you all for your responses. I greatly appreciate it and am happy to have this subreddit.
*Edit: I contacted my doctor inquiring about something I could take that's a prescription to handle the flu symptoms and he suggested 10mg of prednisone prior to the injection. Has anyone tried that or does that to help? Curious about it as I am not a fan of prednisone.
I had a nurse visit scheduled for today at noon. but the pharmacy sent the pens instead of the pre-filled syringes for titration. So I decided forget waiting I'm doing this.
Got it done and over with, drank a ton of water since I saw a few of you say that water helps. Took zzzquil and just went to sleep. I actually feel fine today. Feel a little "woozy" but still feeling fine for the most part. It was scarier in my head then it actually was in reality.
Hi. Gonna do some traveling this december and would like to know how you guys travel with your meds. I'm on Avonex, so I need to pack it with cold packs. Just wondering what is the best way to do so. Thanks in advance.
My doctor has me on Avonex Interferon beta-1a, I've been taking the injection once a week for the past 7 months. My doctor said that these symptoms should get better, and although they are definitely better than the first months, they seem to have made a stop at one point, and I still get weekly fevers.
Can anyone who has been on this specific medication tell me if the fevers get better or not over time please?
I have been on avonex for a while now but my fine motor control and muscular strength in my hands is hit or miss, so it is getting harder to give myself the injection. I called the company to see if I could get the grip and apparently they only give it out with the titration kit but not for those who are already on the therapy.... I was wondering if any of you have tips or products that you use for this situation? I looked into a product called AmbiMedInc Inject-Ease But it seems it was made for insulin and I am not sure if the avonex pre-filled vials will fit the same...