If you're a visual learner, remembering them as quadrants will help with those amino acid replacement questions.
Alternate Polar Neutral: No Quarantine Can Stop You Today!
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Prion aka misfolded protein can survive cooking temperature so cooking does not stop the spread of disease via eating human brain, but how does it survive our digestive system?
Protein -> amino acids -> microvili -> blood vessel -> liver -> spread around the body
Did it just reach the brain as it is, without being changed? How??
The Baker again,
So I'm trying to create a vegan brioche burger bun by reverse engineering an existing ingredient list, I'm unsure of the method and amounts of each ingredient but I do know that the ingredients "Potato Protein and Pea Protein" are included to replace the unique tenderness of egg albumins.
My question is whether pea protein in particular must go through a process not replicable within a home kitchen? or if it is simply hydrated and combined with the other ingredients in no particular order. I know that its use in faux meats require that it is put through a high power extruder.
I also wondered whether replacing a protein is as simple as combining several proteins to match the constituents (In proteins case amino acids) of said protein... I imagine this is a very reductionist assumption, if so what are the other considerations?
Arguably one of the sketchiest things about this diet as a LT WOE for me is the lack of scientific data.
We have bits and pieces here and there, a lot of which goes against the conventional science.
In the process of finding any legitimate concerns with this diet, the only one I haven’t been able to find contradicting evidence or even evidence that would challenge it is the linkage between diets with high amino acids (ZC would top the list) being linked to colon cancer.. the only studies that I can find that would help prevent this outcome revolve around the word Shawn Baker would role his eyes at - fiber.
Can anyone else contribute in any way to this discussion please, it would be much appreciated as a reference to use along the way or even for other to make aware of!
Also, I know I should learn structure, abbreviation, and what group each falls into but do I need to memorize things like pKa or something else?
First some warnings:
This post involves a theoretical reaction with significant scientific backing, some reactions are unverified and may be dangerous. Do not attempt this reaction without significant experience and further research.
This post's main reducing agent is a potentially energetic compound (on the order of RDX, tetrazoles, or nickel hydrazine nitrate) and care should be used when handling it. It has favorable (high temperature tolerance) properties and would likely be a secondary explosive though the energy released from any uncontrolled reaction would be instantaneous (its a polymer) and would involve the release of a toxic, pyrophoric gas, along with an equa-molar amount of hydrogen.
UNDER NO CIRCUMSTANCES SHOULD THIS COMPOUND BE MIXED WITH A COMPOUND THAT HAS STRONG OXIDIZING CAPABILITIES. The energy released by the reaction of hydrogen/oxygen and active boron/oxygen generates enough force to launch rockets (as does active oxygen/hydrazine).
Any attempt to synthesize this compound with malicious intent (utilizing its energetic properties rather than the reducing properties) will not receive a response from me.
This post is going to be quite long as many of my other are so I will add a line (such as the ones above) when I change topics. Enjoy.
So I'm sure many of you have seen my post on reducing agents, (if not you should definitely check it out) and at the end I made a claim about the reducing capabilities of hydrazine, more specifically in the form of metal hydrazides. Unfortunately metal hydrazides are very unstable and cannot be stored. They are also difficult to make (without a detonation) and have unverified reducing capabilities other than catalyst free hydrogenation of alkenes and alkynes (very impressive).
I was researching boron sulfide as a possible reducing agent (dead end) and came across an article that claimed that with heating and high pressures that boron trihalides could be converted to a triamide. This is interesting because boron has trouble forming bonds with nitrogen that are not boron nitride or a lewis adduct.
I then looked into this reaction with hydrazine and found a pivotal piece of literature. The article asserts that hydrazine and boron trihalides react in a way analogous to ammonia and trihalides ([link](https://cdnsci... keep reading on reddit ➡
Could anyone direct me to some figures that would show what is considered risky and low in amino acid intake please?
We (humans) cannot synthetize essential amino acids, at least not as much as we need. One solution is to include in our diet sources of complete proteins and the most popular one is probably meat. This made me wonder, can most animals synthetize all essential amino acids? If so, why are we different in this regard? Is there a significant difference among different species? Does their diet (herbivorous, carnivorous, ...) make a difference?
How I memorize the amino acids using the saints NFL team
Non-Polar (since Winstons grandma is a “Non-player” for the saints) Football Player j.Winstons Grandma Always Visits London In May
Polar (players) Saints Team Crafts New QBs Yearly
Charge (most versatile player T.Hill)
t.Hill Rb Knows Every Drive
Hope this helps ☺️ made this one day when I was watching them play lol
Mine’s cysteine bc disulfide bonds 🤪
I’m in biochem this semester, but we won’t start amino acids for another couple of weeks.
MCAT practice basically requires that I know them, so what should my first step be? Which resources and mnemonics should I use right off the bat?
I understand that amino acids are the building blocks of proteins and everything like that but what is the purpose of taking them rather than protein supplements like whey? Is it just a personal preference thing, is it just so you can get even more protein or is there something else I’m not seeing?
I put a lot of effort and love in making this deck (1) suitable for studying in high school, biology bachelor's, biochemistry, medicine, et cetera. and (2) interesting.
This is the most extensive deck about amino acids on Anki Shared.
The description reads:
This deck will drill you to:
- Know the names of all major amino acids
- Know and recognize all amino acids by structure
- Understand how all amino acids act when built into a protein (Histidine switches proteins on/off in acidic environments!)
- Some memorable and important facts about each amino acid (Did you know that glycine is found in space? That tryptophan glows?)
- Be able to spit out the one letter and three letter codes even if your teacher awakens you mid-night
- Know the charge, polarity and if it's hydrophilic
- If you care - even all the codons for each one (hardcore stuff)
Of course, I recommend suspending some of this info if it's too much. Especially those codons, that is freak-level-stuff.
It introduces a custom note type called "Basic amino acids". The rough skeleton is based on another amino acid deck, and I'd love to credit the dude here (hit me up).
Enjoy. Please leave a thumbs up (means a lot!) before you soak up all that knowledge. And tell me about mistakes or stupid stuff.
Things like Glutamine, Taurine, and others.
have I been sitting here on anki for too long? maybe. but if we can't make an amino acid, ie. an essential amino acid like methionine, how do we start codons?????
edit: ok so apparently since high school biology I have thought that mRNA directly synthesizes amino acids and I have just been informed that all it does is direct where amino acids go. gn
I'm considering getting basic amino acids stack and have a question between these brands and ones from nootropicsdepot
Now's and Jarrow's are fairly cheap, that's good, what about ND quality? Any experience or review?
With the news of the new DeepMind AI that can accurately predict the 3D-structure of a protein; this got me pondering about environmental factors that influence protein structure (e.g: Salinity, pH, Temperature, etc).
Are there examples of proteins with identical amino acid sequences but have a different 3D-structure and therefore the protein acts entirely differently? i.e: A protein in x-conformation acts as a Kinase in one environment but in y-conformation in another environment it acts as a carboxylase. Are these a result of specialized chaperonins?
I don't necessarily mean a protein that exists in both forms in the same organism, but also 2 different organisms and 2 different functions. Any examples would be amazing.
Edit: Thank you everyone for all your thoughtful and scientific responses.
I feel like it’s a bit of a stupid question and people say that “if you have a protein in your diet, amino acids are useless” which I can understand. But buying a crap ton of eggs, salmon and protein shakes can get expensive sometimes. So are amino acids a bit more helpful when a diet doesn’t have lot of protein?
I am doing a project where I want to reconstruct a disease transmission tree using genetic data. I was wondering where I could find this kind of data for a small scale disease outbreak? Honestly, it doesn't really matter what time, or disease it is. It can also be a non-human disease outbreak, but I just need it to be fairly small scale.
Thanks in advance for any help :)
I've recently synthesised a fairly large batch of a hydrobromide salt (35 g) of an unnatural amino acid (UAA). I assayed it on bacteria as want use genetic code expansion to express my protein of interest with it. It doesn't slow their growth at all at the concentrations required but I will eventually move to mammalian expression for in vivo testing, for which I want to desalt it.
For this, the paper used amberlite xad-40 resin, washed out the salts with water, then eluted out the neutral UAA using an ethanol/water gradient. Trouble is, I cant find any protocols for prepping the column, the required mass of amberlite to product etc. Does anyone have experience with amberlite XAD-40 or know of an alternate desalting protocol that doesn't require basic conditions like the piperidine methods do?
Vitamin supplements in question would be amino acids like glycine, or nootropics like citicoline-CDP. I've checked around some Russia online pharmacy sites and couldn't find some of these but others I did.
Can you order American health supplements off of Amazon and have them shipped out to Russia?
Are they already available in Russia?
Can you legally purchase testosterone outright in person at a pharmacy without a prescription?