With next Season only a few days away, today may be the last day to get any meaningful use out of that material.
The rare availability of suitable single‐crystal X‐ray diffraction (SCXRD) structural data allows for the direct interpretation of the response of a framework to gas sorption and may lead to the development of improved functional porous materials. We report an in situ SCXRD structural investigation of a flexible MOF subjected to methane, ethane, propane and butane gas pressures. Supporting theoretical investigations indicate weak host‐guest interactions for the crystallographically modeled gaseous guests and, in addition, reveal that a turnstile mechanism facilitates the transport of alkanes through the seemingly nonporous system. Inflections present in the adsorption isotherms are furthermore rationalized as due to gate‐opening, but without the expected creation of new accessible space.
Journal of the American Chemical SocietyDOI: 10.1021/jacs.1c01524
Jeonghyo Lee, Seongho Jin, Dongwook Kim, Soon Hyeok Hong, and Sukbok Chang
First some warnings:
This post involves a theoretical reaction with significant scientific backing, some reactions are unverified and may be dangerous. Do not attempt this reaction without significant experience and further research.
This post's main reducing agent is a potentially energetic compound (on the order of RDX, tetrazoles, or nickel hydrazine nitrate) and care should be used when handling it. It has favorable (high temperature tolerance) properties and would likely be a secondary explosive though the energy released from any uncontrolled reaction would be instantaneous (its a polymer) and would involve the release of a toxic, pyrophoric gas, along with an equa-molar amount of hydrogen.
UNDER NO CIRCUMSTANCES SHOULD THIS COMPOUND BE MIXED WITH A COMPOUND THAT HAS STRONG OXIDIZING CAPABILITIES. The energy released by the reaction of hydrogen/oxygen and active boron/oxygen generates enough force to launch rockets (as does active oxygen/hydrazine).
Any attempt to synthesize this compound with malicious intent (utilizing its energetic properties rather than the reducing properties) will not receive a response from me.
This post is going to be quite long as many of my other are so I will add a line (such as the ones above) when I change topics. Enjoy.
So I'm sure many of you have seen my post on reducing agents, (if not you should definitely check it out) and at the end I made a claim about the reducing capabilities of hydrazine, more specifically in the form of metal hydrazides. Unfortunately metal hydrazides are very unstable and cannot be stored. They are also difficult to make (without a detonation) and have unverified reducing capabilities other than catalyst free hydrogenation of alkenes and alkynes (very impressive).
I was researching boron sulfide as a possible reducing agent (dead end) and came across an article that claimed that with heating and high pressures that boron trihalides could be converted to a triamide. This is interesting because boron has trouble forming bonds with nitrogen that are not boron nitride or a lewis adduct.
I then looked into this reaction with hydrazine and found a pivotal piece of literature. The article asserts that hydrazine and boron trihalides react in a way analogous to ammonia and trihalides ([link](https://cdnsci... keep reading on reddit ➡
We described a nickel‐catalyzed asymmetric trifluoroalkylation of aryl iodes, by demonstrating the first example of enantioselective reductive cross‐coupling fluoroalkylation with high efficiency, mild conditions, and excellent functional group tolerance, especially for diverse pharmaceutical and bioactive complex molecules. This strategy provided an efficient and facile way for diversity‐oriented synthesis of chiral trifluoromethylated alkanes.
The trifluoromethyl group represents one of the most functional and widely used fluoroalkyl groups in drug design and screening, while the drug candidates containing chiral trifluoromethyl‐bearing carbons are still few due to the lack of efficient methods for the asymmetric introduction of trifluoromethyl group into organic molecules. Herein, we described a nickel‐catalyzed asymmetric trifluoroalkylation of aryl iodides, for the first time, by utilizing reductive cross‐coupling in enantioselective fluoroalkylation. This novel method has demonstrated high efficiency, mild conditions, and excellent functional group tolerance, especially for substrates containing diverse pharmaceutical and bioactive molecules moieties. This strategy provided an efficient and facile way for diversity‐oriented synthesis of chiral trifluoromethylated alkanes.