Visceral adipose tissue plays a critical role in numerous diseases. While imaging studies often show adipose involvement in abdominal diseases, their outcomes may vary from being a mild self limited illness to one with systemic inflammation and organ failure. We therefore compared the pattern of visceral adipose injury during acute pancreatitis and acute diverticulitis to determine its role in organ failure. Acute pancreatitis-associated adipose tissue had ongoing lipolysis in the absence of adipocyte triglyceride lipase (ATGL). Pancreatic lipase injection into mouse visceral adipose tissue hydrolyzed adipose triglyceride and generated excess non-esterified fatty acids (NEFA), which caused organ failure in the absence of acute pancreatitis. Pancreatic triglyceride lipase (PNLIP) increased in adipose tissue during pancreatitis and entered adipocytes by multiple mechanisms, hydrolyzing adipose triglyceride and generating excessive NEFA. During pancreatitis, obese PNLIP knockout mice, unlike obese adipocyte-specific ATGL knockouts, had lower visceral adipose tissue lipolysis, milder inflammation, lesser organ failure, and improved survival. PNLIP knockout mice, unlike ATGL knockouts, were protected from adipocyte-induced pancreatic acinar injury without affecting NEFA signaling or acute pancreatitis induction. Therefore during pancreatitis, unlike diverticulitis, PNLIP leaked into visceral adipose tissue can cause excessive visceral adipose tissue lipolysis independent of adipocyte-autonomous ATGL, and thereby worsen organ failure.
Keywords: Adipose tissue; Fatty acid oxidation; Gastroenterology; Inflammation; Mouse models.
New study shows unsaturated fats (oleic, linoleic), in olive oil, 'vegetable' oils causes organ failure during acute pancreatitis. Belly fat rapidly degraded. Body can make some oleic but not linoleic. Study took 7y. to do
I have struggled with some form of addiction most of my life. Alcohol in the past 5 - 6 years, and very heavy use for the past 2 or so. I went to the ER with severe abdominal pain and found out my pancreas was extremely infected and a small part was in a state of necrosis ( dead or decayed.) I am know pretty much forced into sobriety at a relatively early age if I want to lead a healthy life.
so i had AP back at the very beginning of july and was in the hospital for 5 days on a steady diet of dilaudid and iv fluid LOL. that pain was unbearable and felt like my insides were turning inside out (graphic for no rzn i’m sorry lmfao) HOWEVER since then ive been having on and off discomfort. sometimes its worse than others but its always discouraging because i feel as though i’m getting better and then BOOM mr pancreas is angry again. the pain hasnt been as unbearable but its certainly been kinda bad a few times since my attack- but mostly just mild discomfort and never bad enough to where i think i need to go back to the hospital.
is this just apart of recovering from my AP? or is this repeated discomfort an indication of developing chronic pancreatitis?
btw ive been on a strict low fat diet (no more than 15-20g of fat a day MAXIMUM), have lost about 20 pounds and seem to be more lethargic/ out of it since my AP.
Hi, I have to wait 10 days for my endoscopy, and then surely more time after for a follow up appointment. I have a sour stomach that is really intense. I've had burning gnawing tummy feelings before but this is new. Is there anything over the counter that might help while I wait? It only abates when I eat and I can't eat continuously as much as I'd like to. I'm on 50mg daily dose prilosec. And I'm eating the anti-inflammatory diet already. Thanks in advance!
To preface I used to be an extremely heavy drinker and was killing about a handle of gin a day with some bud light platinums also. I started to experience discomfort in my abdomen in January of 2019 and would drink to attempt to numb the pain. This worked at first. Then on February 11th 2019 I woke up in searing pain in my upper abdomen to the point where I immediately knew I had to get to the ER, my dumbass knew I'd likely be there at the very least all day so I chugged some wine to try and help the pain as well as get me through the day. Horrible idea. Immediate vomiting and extreme intensification of pain ensued. I then have my mom take me to the hospital (22 at the time), the whole time I keep thinking about how pain that bad couldn't exist. I get seen within 5 minutes and they start running tests on my heart, it took about 3 hours for them to even run any tests besides an EKG due to the ER having a lot of cardiac arrests going on. I get a CT scan and it shows severe acute pancreatitis, I finally then am placed on morphine which did literally nothing. I was admitted and spent the next few days in intensive care until I was more stable and got moved upstairs for the remainder of my stay. 16 days of withdrawals while dealing with immense pain (which did get a little better after I was heavily drugged) and getting MRIs and CT scans almost daily. Developed a fairly large pseudocyst and had to be placed on a picc line, I had to go 30 days without eating anything. This experience is something I wish no one would ever have to go through, I have not and never will touch alcohol again. To this day I'm healthy and pain free. I just wanted to write this because when I was going through it I came here scared to death not knowing if I'd ever recover.
This is my first post in this sub. I feel like I need to share my story because none of my friends or family members have ever experienced what I'm feeling. I have developed acute pancreatitis through my excessive use of marijuana. I use it recreationally and to calm anxiety. There are many factors in play such as how frequent, how long and what form of cannabis you are using. I was always a flower vaper using my "Mighty" vaporizer and I've never had any health issues. Upon 2020, I've picked up a habit of dabbing all forms of wax, oil, diamonds, dab pens, you name it, chances are I've been using it.
I checked myself in to the walk in clinic the other day due to cyclical vomiting and uncontrollable nausea. All my blood tests came back normal except for amylase in my liver which was about 3 times normal level. I even got an x-ray to check for blockages. Stupidly enough for me, I have had these issues going on for about 3 years now, but the symptoms are essentially 0 in the months where I am only smoking/vaping flower or an occasional edible. Although in order to get back to using flower, I need to cease THC consumption entirely for several weeks. I'm not going to get into the science behind it mainly because it is not fully understood and I don't fully understand it. I've done a fair amount of research online about pancreatitis linked to THC and more research about cannibinoid hyperemesis syndrome (CHS).
Has anyone else experienced this? Am I right in thinking that the potency of the THC in dabs is the culprit? Are there other factors in play such as the quality of the plant, potential mold or possibly pesticides.
TLDR:. I developed acute pancreatitis or (CHS) through excessive use of marijuana oils and I'm suffering from daily nausea and vomiting... I just want to eat solid food again
I used to drink a LOT. Most likely the main reason I got in this predicament. I was in the hospital for about 3 days after an "attack". The first and only time I've had an issue like this. Haven't drank since. When I got out, I was taking it easy, trying to eat as low fat as I could, etc. But I'm back to eating normal now. Ice cream, chocolate, whatever food I want and no issues. Wondering if drinking is completely off the table. Like, if I have a shot or two, will that just fuck up my shit again? Previously, I was drinking a pint of vodka a night or more and double that on weekends. I've been pretty happy being sober but just wondering if having a bit here and there will screw me over.
Edit: This is the info from my CT Scan: IMPRESSION:
Also, here are the 2 lipase results. The higher number is the first test: https://i.imgur.com/9fDmggW.png and then https://i.imgur.com/mSii8BT.png. I didn't see any amylese or whatever it's called tests or results.
So recently doctors found out that i have acute pancreatitis but they dont know how i got it i have been drinking only for 4 moths but not too much 2-4 beers per day.Anybody here got the same problem i need to know if i can drink like 2-3 times a year.Im 17 and i got pancreatitis 9 months ago.
If anybody knows if i can drink ever again that would be helpfull.
Has anyone waited six months after pancreatitis and started drinking again with no complications ?
So I’m like 99% sure I developed it yesterday and It was freaking awful but I told myself I would only go to the hospital if it felt the same or worse the next day. Well the constant pain is gone, now it’s only if I eat or drink does it hurt. If I am able to not get super dehydrated, can I just deal with it on my own?
Hey guys, would you please share your points about Bilirubin levels, ALKP, LFTs, Amylase, Lipase, best option for diagnosis and best treatment options for above Dx. I am answering all of related questions wrong😭 TIA
Hey, this is my first time posting here after mostly lurking and upvoting posts.
I need advise on how to recover and avoid future pain. After experiencing some pain, I stopped drinking for almost two weeks. After 3 days of drinking around 4 units each day, the pain returned.
I have since stopped drinking again. This was the first year that I drank heavily or binge drank.
I figure I may need 1-3 months to fully heal, I read one UK article that recommended 6 months of abstinence.
Wishing everyone the best. Chairs!
EDIT: Pancreatitis is no longer the issue but they found sludge in the gallbladder and my liver function is poor suddenly. They told me to stop eating so I've been on liquids since Saturday and my lipase are normal finally as of today but I'm nervous I will get sick again if I start to eat solids.
They asked me about drinking and high fat consumption. I almost never drink, less than 4 times a year and I havent been intoxicated since 2016. I used to have a somewhat higher fat diet but nothing crazy. That being said, I've been on a low fat high fiber diet per my GI as I have recently been diagnosed with Eosinophilic Esophagitis and am on a restricted elimination diet.
I've have a few episodes of vomiting, diarrhea, stomach pain, and other general unwell symptoms. I've been to the ER twice and they do a CBC and basically tell me to drink more water.
This time the ED Dr tested lipase and told me I had acute pancreatitis. Was given zofran and fluids and I have been taking tylenol for pain. I feel 100x better but this has been a problem for about 8 weeks now of varying degrees.
If I dont have gallstones, family history, or drink to excess- why would this happen? Is it possible they were wrong?
Hey guys, new to this sub so just looking for some support really.
I had an acute attack about a month ago... I'm 21/F and used to drink moderately-heavily, not really care about diet etc. Spent 4 days in the hospital on an IV, found out that although there were no gallstones I have a thin lining around my gall bladder and my lipase was high, around 1200.
Firstly - can someone explain the role of lipase and how this will contribute/indicate pancreatitis? As I'm not really sure. Same with my gall bladder being thin?
Since leaving the hospital, I have quit drinking alcohol completely and adhered to a low fat, low salt, low sugar diet and reduced animal products to basically eating vegetarian most days. However I'm still experiencing pain most evenings - could this indicate that I may develop chronic pancreatitis? Or is this just my body healing from the attack?
I'm so new to this and trying to learn how to keep myself healthy and as pain free as possible - I'm needle phobic so the thought of being on another IV or possibly needing surgery terrifies me. So any and all advice would be greatly appreciated please.
Thanks in advance ❤️
So I just got out of being in the hospital for 2 days from pancreatitis I got from drinking too much during quarantine. It's looking like I can't really drink again. Which sucks, because I like beer, the culture around it, and the act of drinking with friends. Anyways, besides weed, which I already smoke, what is a good alternative out there that I can take when out with friends that would make me relaxed, sociable etc.... I was thinking about kava since it's popular where I live and can have that social aspect as well when you're drinking it in a group
I got diagnosed with Acute Pancreatitis after spending a couple weeks vomiting at random times a day and having zero appetite. I went to the doctor and he checked my enzyme levels, and sure enough, they were very elevated and he gave me the diagnoses over the phone with the instruction to go on a clear diet.
I don't feel great, but I haven't thrown up all day, and weirdly I had no pain at all yesterday, but started to get a dull but mild pain in my back that has stayed consitantly mild all day. I'm bloated af.
Of course I read the internet and every single website recommends hospitalization, and one even said that for some people, the pain will delay itself for a couple of days before beginning.
I have an appointment in two days. I'm getting tested for gallstones next week and going to get a CT scan. I don't intend on eating anything or drinking anything but juice, water, and electrolytes.
So now I'm all freaked out. Did he have me stay at home because we got ahead of it by catching it early and I didn't have any pain? Does the pain typically get worse? Have any of you ever had a more mild experience and just stayed home?
I had my first AP attack last November. I remember being in so much pain that I absolutely had to go to the ER because I had no idea what was happening. At the hospital, they gave me morphine but it barely even touched the pain. I remember that the pain would be really intense and then for a few minutes I would finally feel normal.
Well, about two weeks ago, I had extreme nausea, vomiting, discomfort, and insomnia. The only other time I had experienced those symptoms on that level was when I had my first AP attack. However, I had no pain whatsoever, so I ruled AP out. I talked to my doctor about my symptoms and she confirmed that I probably didn’t have it because I wasn’t experiencing that excruciating pain. She also told me that if I ever get it again, I can set up an appointment and she can prescribe me some meds, so I wouldn’t have to go to the hospital because of this pandemic that is going on. Well right now, I’m experiencing extremely bad back pain and a little bit of stomach pain. I think I may be having an attack right now. I took Ibuprofen, and since then, the pain has been coming and going. I just wanted to know whether anyone else has had AP and had it treated at home. What was that experience like? It’s late at night where I live so I would not be able to talk to my doctor until tomorrow, but I can’t imagine being in that much pain and not going to the hospital.
On Saturday, so a few days ago, I went to the hospital because of blood in my stool and persistent (almost 3 weeks) stomach pain. I've had one diagnosed pancreatitis episode in the past, 8 years ago right before college graduation. This time it felt different though. Back then, I had pain in my upper abdomen that radiated to my back, I lost my appetite and I couldn't move because of how severe the pain was. This time, I was biking 12 miles to the wine store, three days a week. I was able to stand up and help with chores in the apartment. The feeling in my belly was more annoying than it was painful. Truly, it was the blood in the stool that got me to reach out to a doctor, who advised me to go to the ER. I had been putting it off, like most people these days, because of COVID-19.
They only kept me there for a few hours. They said that they usually keep patients for days to monitor, but in my case, because I seemed stable, I could go home. In college, I was in a hospital bed for almost a week, with pain medication and fluids. Though they sent me home this time, they did link me up with an associated GI, who reached out to me next day for a video chat. He told me to stop eating anything solid for a few days, to avoid fats and sweets, and all that. That was yesterday, so I've had plenty of small, bland, slurping meals since.
I still don't know the extent of the damage from this episode. My stomach feels almost completely okay right now. I am so thankful for that, because my last attack had much more prolonged pain (3-4 months). Still, I won't be happy or feel comfortable until all tests are complete and I get a CT scan done. I am worried, because as a wine professional, I've had wine everyday for almost a decade. Sometimes a little, sometimes A LOT. I am not a smoker, but I've also socially smoked throughout the years.
My next video chat with the doctor is tomorrow, and while researching this disease (in order to find all the questions I need to ask), I stumbled upon this page. I didn't have a Reddit account before this one, which I created 10 minutes ago. I read some of the posts here, and instead of the awful, terrifying words that I'm used to reading regarding pancreatitis, I found encouragement and hope. I immediately walked into my bedroom (where my fiancee is working remotely) and told her that I felt better. She's very worried about me. We're supposed to get married and have a long beautiful life together! Reading some of your posts here have... keep reading on reddit ➡
So like the title says I was recently diagnosed with acute pancreatitis from alcohol this past Monday. I was only in the hospital for 4 hours hooked up to an IV and pain medicine. I left the hospital and did the liquid diet the rest of Monday, the rest of this week I’ve been able to keep down solids that was recommended to eat. I’m just really confused what this actually is, I know it was from drinking and I have to eat low-fat foods I get that, but from what I’ve read online confuses me, will I have to deal with pancreatitis the rest of my life? I thought if I followed the steps and it went away I’d be fine, I see people online saying they get it every year or so? Also do I have to eat a low-fat diet for the rest of my life as well? And will acute flair ups kill me if I get them a couple times? Sorry for all the questions I’m just freaking out and I don’t have a follow up appointment with my doctor until next week. The ER never told me this is something I’d have to deal with the rest of my life.
Dunbar RL, Gaudet D, Davidson M, et al. Omega-3 fatty acid exposure with a low-fat diet in patients with past hypertriglyceridemia-induced acute pancreatitis; an exploratory, randomized, open-label crossover study. Lipids Health Dis. 2020;19(1):117. Published 2020 May 30. doi:10.1186/s12944-020-01295-7
Background: Omega-3 fatty acids (OM3-FAs) are recommended with a low-fat diet for severe hypertriglyceridemia (SHTG), to reduce triglycerides and acute pancreatitis (AP) risk. A low-fat diet may reduce pancreatic lipase secretion, which is required to absorb OM3-ethyl esters (OM3-EEs), but not OM3-carboxylic acids (OM3-CAs).
Methods: In this exploratory, randomized, open-label, crossover study, 15 patients with SHTG and previous AP were instructed to take OM3-CA (2 g or 4 g) and OM3-EE 4 g once daily for 4 weeks, while adhering to a low-fat diet. On day 28 of each treatment phase, a single dose was administered in the clinic with a liquid low-fat meal, to assess 24-h plasma exposure. Geometric least-squares mean ratios were used for between-treatment comparisons of baseline (day 0)-adjusted area under the plasma concentration versus time curves (AUC0-24) and maximum plasma concentrations (Cmax) for eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
Results: Before initiating OM3-FA treatment, mean baseline fasting plasma EPA + DHA concentrations (nmol/mL) were 723 for OM3-CA 2 g, 465 for OM3-CA 4 g and 522 for OM3-EE 4 g. At week 4, mean pre-dose fasting plasma EPA + DHA concentrations increased by similar amounts (+ 735 - + 768 nmol/mL) for each treatment. During the 24-h exposure assessment (day 28), mean plasma EPA + DHA increased from pre-dose to the maximum achieved concentration by + 32.7%, + 45.8% and + 3.1% with single doses of OM3-CA 2 g, OM3-CA 4 g and OM3-EE 4 g, respectively. Baseline-adjusted AUC0-24 was 60% higher for OM3-CA 4 g than for OM3-EE 4 g and baseline-adjusted Cmax was 94% higher (both non-significant).
Conclusions: Greater 24-h exposure of OM3-CA versus OM3-EE was observed for some parameters when administered with a low-fat meal at the clinic on day 28. However, increases in pre-dose fasting plasma EPA + DHA over the preceding 4-week dosing period were similar between treatments, leading overall to non-significant differences in baseline (day 0)-adjusted AUC0-24 and Cmax EPA + DHA values. It is not clea... keep reading on reddit ➡
Hey all, astounded sufferer of AP, and profoundly freaked out.
I have no obvious risk factors--my diet is balanced, I don't drink or smoke, and there's zero history of gastrointestinal issues on either side of the family. 35, male.
Yet last week, poof, there it was. It felt like gas pains at first, but within 30 minutes the, god, outright REMARKABLE degree of pain would make me pass out. In hindsight, maybe it was the labored breathing? At any rate, I was sure I was dying without knowing why.
(The pain is a fifth-dimension experience; seriously, I'm a big guy, covered in tattoos; have been stabbed, hit by a car, electrocuted, broken multiple bones--the pain of that first day made me want the comfort of a teddy bear.)
My lipase level on admission was 9652u/l. No one explained this to me, but that's... that's pretty high.
Over the course of a week, I had every test, scan, and lab they could conjure. A police sketch artist even produced a portrait of a wrathful pancreas. It was wonderful. A true likeness.
Okay okay, they didn't find anything. For days there was talk of removing the gallbladder, but after injecting radiation and sailing a gamma camera over me on the last day, the doctors sort of tossed up their hands and were like, "well, we'll get 'er next time."
And out I went, back to my regularly scheduled programming.
So... what the hell just happened?
It's been about 30 hours since I was discharged. I've barely eaten--both from lingering discomfort that raises its head when I do and from fear I'm going to piss off that wrathful pancreas. Trust me, if you'd seen the picture, you wouldn't want to piss him off, either.
And what's next? While each doctor, surgeon, and specialist gave me a lot of information, there wasn't anything about what to expect. Eat a little less of this. See your PCP. Quit carrying around that awful drawing.
While they performed ultrasound, CT and HIDA scans, and a battery of blood and urine labs, they didn't x-ray the area or conduct an MRI--would either of these turn up something the others couldn't?
The picture is of a guy who just experienced the first thing he could describe as agonizing while letting the understatement of it ring true. He has no idea why this happened, and would like to request, kindly, that that it doesn't happen again. He still doesn't know if he's dying; he wonders: cancer? Coronavirus? Disco Fever? He's eaten much apple sauce. He's still in pajamas. He is holding a blob of scribbles that he c... keep reading on reddit ➡
So...my husband is an alcoholic. We have been married 15 years this year. It seemed to start gradually... 1 more drink when he got home to 2-years later—- Gatorade and vitamin water bottles filled with pinnacle vodka strewn all over the house and car.
He stopped being a dad and father about June 2017. No involvement, just drinking. Occasionally if he was awake after school he would shoot a few hoops with the kids.
He was able to go to work and bring home a paycheck. He lost his job in November of this year. More recently this year he became increasingly paranoid about what the kids said to him. He would say that I was spreading poison about him though it wasn’t true. He stopped attending any family events or social events.
He showed up completely drunk to our 14th anniversary getaway with our children. He spent three days in bed complaining of stomach pains.
I reached out to his parents and sister over the year through email in March, June and November and they did not respond. (His mother and sister are also alcoholics).
On December 21st he went to the hospital with severe pain. It was acute pancreatitis caused by long-term alcohol abuse. He was treated for that and then 10 days of Ativan-induced detox. He almost had to go on a feeding tube.
5 days in... his father showed up and threatened me with a power of atty and told me to leave. Unbeknownst to me, my husband had signed a POA with his dad (an Atty) for both medical and financial reasons. I am still unsure of why he signed those documents.
I work full-time and take care of all the household bills, all household items— cleaning, cooking, shopping, kids activities and everything else that comes with managing a household for 5 people.
The kids are 11, 8 and 6. They have lived in this stressful and horrible environment for years now.
He’s in rehab but still unable to take responsibility for anything. He blames it on anything... me, the kids, financial pressure. Anything but himself.
I don’t know what the next step is for us but one thing I do know is that I will no longer live with an alcoholic.
I hope he recovers, I hope he’s around a long time for the kids... but it just might not be in a marriage with me.
I'm curious to hear from those who don't have the usual causes of AP such as excessive alcohol or gallstones.
I'm a 55YO male who was hospitalized over the weekend for a second bout of AP in nearly two years.
The first was in May 2018 when I checked myself into ER for severe abdominal pain. A CT scan showed no gallstones but an inflamed pancreas. Lipase levels were >2250. Around the time my drinking habits was around a glass of wine with dinner about three, four at the most, times a week. Test showed my triglyceride levels were normal. I spent two nights in the hospital where I was given IV fluids and not allowed to eat or drink for most of the stay. The attending physician described my case of mild.
The diagnosis was idiopathic pancreatitis with no necrosis or infection.
Fast forward to this past Friday. While at work that morning, I began experiencing abdominal pain which just got worse and worse. Finally, I couldn't take it anymore and told my boss I wasn't feeling well and was leaving for the day. I then headed over to the ER of a nearby hospital. I was diagnosed with AP through a blood test which should lipase levels of ~7000. An ultrasound showed no gallstones or biliary dilatation. Again, triglyceride levels were normal. Alcohol can not be a factor since I pretty much gave it up after my first incident. The last time I had alcohol was a glass of wine at Christmas. As in the last time, I spent two nights in the hospital where I was given IV fluids and was limited to clear liquids. The hospital is still waiting for lab results for igG subclasses and tissue transglutam which may show if my AP is caused by some sort of immune disorder or celiac. I was also told I would be contacted to setup an appointment with a GI specialist where I would have either an MRI or endoscopy performed on me.
Some other info about me. I'm adopted so I have no knowledge of family history of pancreatitis. I currently do not or have ever smoked, or used any recreational drugs. I don't take any prescription meds and only occasionally take Ibuprofen on an as needed basis.
So until the pending lab results come back and my GI appointment, I would like to ask those to whom this post is directed at, what did end up being the cause of your AP. TIA
My husband is having dull pain in the stomach since 2017. He went to the ER once every year since then. but he was never diagnosed as pancreatitis until recently. On the 7th of Jan, he was having a sharp stomach ache not radiating to back. one he same morning he was having this pain and he went to ER, they did blood test lipase was 38 and ultrasound was normal. they send him home. In the evening I made him eat spicy and oily food and after eating that his pain starts. We went to the ER and his lipase was +9000
MRCP shows mild inflammation of fat cells around the pancreas and non-alcoholic fatty liver disease. He was given liquid on 9th and soft food on the 10th and got a discharge. Surgeons are recommending laparoscopic cholecystectomy in case of microlithiases, though nothing was there on MRCP. I will followup GI in the coming week.
This blood test on 13th shows 98 lipase and liver enzymes are also getting better. He is on bland diet and i am taking care of 20mg of fat per whole day. His BMI is 34.
I wanted to ask, is there something i can do to stop future flare?
I have chronic idiopathic pancreatitis ---- we don't know what caused it, I have intermittent flares usually more related to food consumption and stress than anything else. Although I live with a pain level of 2, I have no fever or other indications of being "ill" or having an infection. I take no routine medications other than melatonin to help me sleep past the pain.
My geographical area is experiencing a shortage of blood donations --- I used to donate regularly so they're calling my house phone and sending me postcards. I can't find anything on the Red Cross website that says "no" to folks with chronic pancreatitis, but I was hoping to get some experience from other sufferers who may have opted to donate blood since diagnosis.
Hi can someone recommend me a good, up to date source to study pancreatitis (maybe a guideline from the American College of Surgeons or the American Gastroenterological Association). I’ve tried looking up on google but nothing good game up. Thanks in advance.
I recently moved across the country so I am seeing a new gastroenterologist this week. I’m bringing records from my last one but it’s just the tests he did that were negative. We were trying to figure why I kept having these attacks. Don’t drink, gallbladder was clear, nothing showed up on the endoscopic ultrasound, HIDA scan was good and no autoimmune disease. I haven’t had a major attack since last April but I definitely have had bouts of what I would consider mild pancreatitis type pain.
I guess I just want to know what would be wise to ask? Is it unreasonable to be like “hey, can we start from the top?”
All the doctors I saw in FL were always like “sorry, we don’t have any answers. Hope you feel better soon!” I’m terrified to get brushed off again.
I am devastated, depressed, despondent. I’ve worked in the restaurant industry for almost 16 years and in wine for 7—obviously my favorite 7 years! I don’t know how to do anything else, nor do I want to. Just fucking broken now ...
Hi, everyone. I'm a 22F who just got a call from her doctor yesterday telling me that my lipase levels are 3x the normal amount, and he diagnosed me with pancreatitis. I've been vomiting almost everything I've eaten for over a week, so I guess I'm glad to have some answers. He told me to stay on a clear liquid diet in the meantime until we find out what caused this. I had an ultrasound, too, but I'm still waiting on the results from that. My gallbladder looked like it had a few polyps or something, so the waiting is killing me.
I'm not a big drinker (like 2 glasses of wine each month at most), but I went to a wedding a few days before this all started, and had hard liquor for the first time in years. Part of me worries that this is all my fault. But I've never been overweight, I eat better than most people I know, and I exercise frequently. I know that I have to wait until I hear about my ultrasound results for next steps, but I'm just so depressed with this diagnosis. It seems like everything I've read online is telling me that my life is going to be different from now on, and I'm not sure what else I can do besides... not eat. So, I guess I'm wondering: what should I expect from here on out? What are your lives like before and after this diagnosis? Is it really that serious or can I keep on living the way I was before? I just feel kind of lost.
Bio: 26 Year old Caucasian Male, 5'9" 250 pounds. Never had any physical health issues I'm aware of even when morbidly obese. Probably had depression during obese years however never officially diagnosed. Drink on very rare occasion (probably once every 4 months, and it's casual not heavy). Don't smoke. Haven't taken any pain meds in the last year. Got a ingrown toenail removed in August and was perscribed Amoxicillin K Clav which supisingly to me had an allergic reaction to Amoxicillin (never happened before).From September-December didn't have insurance because of getting kicked off parents plan at 26. Will have obamacare starting Jan 1.
Concern: Something in upper left abdomen area is messed up. Feels like a knot and when things were at their worst had nausea, loss of appetite, shortness of breath, barely could eat 150 calories in a day without severe bloating. Also had pain in upper right abdomen as well during some episodes. Symptoms are less now, but still experience constant dull pain in the pit of stomach feeling on the left side. Eating always feels uneasy. Drinking water currently is ok but not great. Always burping no matter if I eat or not.
Hey everyone. So to begin, I used to be morbidly obese (405 pounds). March of this year I finally decided enough was enough, to finally get out of the depths of depression I was experiencing during that time from various factors that started to impact on each other (being overweight/obese my whole life, family problems that occured earlier in life but have really affected me to this day, which lead to me not caring about school/dropping out of college, etc.). The only reason I finally had the courage and perserverance to lose the weight because I had enough of being depressed and feeling like nothing would ever get better, and just wanted to see if I stuck to one thing, could it possibly be my glimmer of hope in life to finally find happiness.
Fast forward to present day and I've lost 155 pounds. Everything seemed fine and the progess of my weight loss was just amazing, until mid-November of this year where I decided to scale back a bit on my diet, not only because the holidays were coming up but I felt my current diet was just not sustainable for my whole life and eating relatively normally again would be a smooth transition.
To give an idea about my regimen for my diet from March-November, it was 1200-1500 calories daily. 3-5 mile walks daily. I wasn't super strict on fat/carb intake with my diet meal... keep reading on reddit ➡
(crossposted from /r/pancreatitissurvivors for activity reasons)
I (24M) started having stomach troubles and bloating last week, leading to the onset of pain on Sunday, and a blood test on Tuesday. That blood test had me at a lipase levels of 1195 U/L, which seemed scary high to me.
My doctor, subsequently, sent me for a CT and ultrasound, which confirmed a few things: first, “minor” inflammation of the pancreas; second, an inflamed/enlarged spleen (15cm!); third, a gallstone of roughly 2in that’s mobile and was not observed to be blocking anything (at the moment).
So, since Tuesday, I’ve been lazing around, trying to keep right. I tried with slices of bread Wednesday and Thursday, but was told to go clear liquid only for a bit. The pain does seem to be responding to that shift, and the Vicodin doesn’t hurt.
What brings me to you all is the hope of advice for how to handle the next few days/weeks, and what timeline I should expect for recovery. As of yesterday, my lipase count was down to 950, and the pain has been down to tolerable, if uncomfortable, levels. Generally, how long has it taken for you all to bounce back? Christmas is big for my family and I’d love to be able to at least eat something with them.
As for long term concerns: I am not an alcoholic nor do I even drink very much at all— just socially, and rarely to excess, maybe a handful of times a year. Occasionally, a single beer or glass of whiskey or wine every few weeks. I am not obese, though I do admittedly need to lose some weight (I’m a short guy at just under 170lbs). My diet could be better, but I wouldn’t call it terrible.
It seems, so far, that this leviathan of a gallstone is to blame (triglycerides were very good, which is a silver lining here). What should I anticipate for lifestyle impact? Is it possible that I can still enjoy a beer every now and again, or a steak?
Sorry for the ramble, the last 48 hours have been scary for me.
Current medication : 20mg omeprazole /20mg ranitidine for reflux/ibs.
Cholecystectomy 3 years ago. Have 'mild/moderate' hiatal hernia.
Pain started last night
7.30pm Took 60mg codeine for headache
8.30pm epigastric pain started, ate light meal
9.15pm pain peaks, would call severe and stabby/bloated, vision blacks out for 10 seconds, sweating a lot
10.30pm pain has settled enough to sit up
1am vomited undigested food.
Overnight was difficult to sleep. Pain now more dull and crampy
It's 3.30pm the next day and still have moderate epigastric pain that occasionally goes around to my mid back. Feel nauseous and shorter breathing as deep breaths make pain/cramps worse. Feel a bit weak. Normal temperature, have tolerated moderate amount of water without vomiting. Blood pressure a little elevated according to home machine. Does this sound like pancreatitis? The severe pain only lasted less than an hour. Have read codeine can cause it in people without a gallbladder. Seeing how the pain is now tolerable would it be OK avoiding the ER? It's very overloaded as expected in my area right now. Should I avoid eating any solids for today? Any other suggestions? Thank you
I am a 28 year old male. This past weekend I over-indulged in alcohol and it triggered my first ever episode of acute pancreatitis. I probably had about 7 drinks on Saturday. However, it is very rare for me to ever drink that much. I consider myself a moderate drinker, as I usually have a beer with my meal at night and then maybe a whiskey night cap. Some days I don't drink at all. On the weekends I tend to drink more, but not by much.
Anyways, after my episode, I stayed at the hospital for about a day and a half and my lipase levels normalized after about a day. So it wasn't terribly severe.
The hospital did not tell me to stop drinking forever, but what I am reading online is really discouraging.
Will I ever be able to drink 1-2 drinks a day in the future or ever be able to drink hard alcohol again?
I had no idea I was at risk for pancreatitis. Really wish I could have been educated better on preventing it.
Hey everyone! Some background; Im a 20 yo male that drinks once every two months (at worst)
I just had my first episode of pancreatitis a week and a half ago. Classic symptoms of abdominal pain, bloating, nausea, but also I had strep throat so I was on penicillin. The reason for the pancreatitis was that the penicillin had killed most of the bacteria in my guts which put heavy strain on the pancreas to digest. For the first 3 days it was painful (and i took my medicine) but it felt better after that. I didnt eat for a couple days and started with soft foods.
Anyway, fast forward to last week I drank two cups of liquor celebrating an occasion and felt bad the following day as if my pancreas had flared up. I thought my pancreas would have been healed by then. I was in pain for about 3 days after that, then it subsided.
Now all of a sudden I am starting to have the same pain in my upper abdomen (albeit milder) and my bloating still has not gone down.
Should I be worried? And should I schedule to see a doctor (min 7 days before an appointment), or go to the urgent care/er? Things I could do in the meantime? Has anyone experience anything alike?
24 (F) 5'3 125 lbs, Latino
I have a concern involving possibly my gallbladder and pancreas it feels like I got kicked by a horse in my middle abdomen and it goes through to my back and wraps around my right side I also experience sharp pains on my right side it's to the point where it's hard to breathe or do anything like standing is even a chore at this point it's gone on for about a year but has progressively getting worse what should i do? Should ni see a doctor or go to the hospital?
I do smoke
My boyfriend has had a couple acute episodes in the past year that have been set off by fatty food. I’m not a cook and I have always done preprepared “heat and serve” Thanksgiving meals but I didn’t purchase one this year since the majority of what comes with them he can’t eat. I’m still trying to make Thanksgiving special though and I’m having a hard time finding recipes for side dishes he’d be able to eat that are easy for someone who isn’t familiar with cooking.
I see turkey breast is okay as the main meal. I’m thinking I’m going to do canned cranberry sauce with it. It seems like potatoes are also alright as long as there’s no butter (so maybe fat free sour cream?) and fruit. Does anyone have any recommendations for other dishes I could make? Thank you
Sitting in the hospital as I type this.
Symptoms came out of nowhere, my fiancé and parents both thought it was just the flu. I had to leave work and call out for two days before they realized I wasn’t just being a baby.
Ridiculous pain in the abdomen, constant nausea (couldn’t even eat ice chips without throwing up), crazy cramping of the abs, and IBS like you read about.
I’m a former bing drinker, but I’ve cut down HEAVILY over the past year (maybe one drink two nights a week), have a really good diet, my liver came back clean as well, but I assume there’s no other explanation.
It’s been 6 days since a bowel movement, they have me on a dilauded, laxative, anti nausea, stool softener routine with a liquid only diet.
Obesity is a medical condition where excess body fat has accumulated in the body to an extent it can have adverse effects on our health. Obesity, as we all know, brings a wide spectrum of health risks such as cardiovascular diseases, diabetes, hypertension, gallstones, respiratory problems like sleep apnoea, asthma, etc, all termed as comorbid conditions or comorbidity. Added to the list of risk factors, obesity can also contribute to a common yet fatal condition known as acute pancreatitis. Here is more. https://springfieldwellnesscentre.com/the-connection-between-obesity-and-acute-pancreatitis/
Mail us at [email protected]
#Obesity #Pancreatitis #MetabolicSurgery #DrMaran #SpringfieldWellnessCentre"
My girlfriend, who is in her early fifties, suffered two bouts of acute pancreatitis due to drinking, about three years ago, and about six months apart. Each required hospitalization, fluids and pain medication, and eventually cleared up.
She's since been sober, and has had no further problems. She's also cleaned up her diet, started exercising, and is taking good care of herself. My question is, has she done herself any long-term damage? I tried researching this myself online, but I can't seem to find any clear answers. Are there any? What are the long-term effects of a couple of acute pancreatitis episodes?
Now I’ve done it. I’m having an acute pancreatitis attack and I just have to deal with the blinding pain. It’s been 24 hours since I took the Nal so I think I have another 48 until the morphine will work.
It’s a good wake up call. I’m 8 weeks in but I think I was losing sight of how vital it is for me to kick this. I need to be more proactive in my extinction of the craving. I need to frigging just drink less! I think I’ve been letting myself off the hook a bit while I “let the Nal do its work” because it means that I get to drink.
Ibuprofen doesn’t even touch this pain. I’m fasting so hopefully I can get this pain under control that way. Thanks for listening.
Hi I had acute pancreatitis 2 months ago was in hospital with it and had get my gallbladder removed as gallstones what was causing they think but I also was a big drinker which the Dr did tell me to avoid after my surgery and been off it since been so hard though but I decided there on Friday night I would have one beer and on Saturday night I'd have one beer and thought surely one beer can't do much harm and boy was I wrong had another attack last night same pain had couple months ago thought I wouldn't get it again since gallbladder removed but I did and had really bad pain in back and really worried now is this all cause had a couple beers it's so difficult not to ever drink again I'm only 24 and been such a big social part of my life I just don't what I'm gonna do but if my pancreas is gonna flare up everytime have one drink then there's no way I can I'm so worried now just hope I be ok don't wanna have go back hospital again and I don't no what they could do about it need here some other people who r in similar situations as me really need some help x plus does anyone know if cannabis effects the pancreas ? As had a joint yesterday to for first time in years
Like the title says, I'm a male, 28 y.o., 5'9'', 165 lbs, NKA, no meds or OTC, former smoker/former drinker (15 months off both), no recreational drug use, hx of acute pancreatitis with ARDS.
I'll try to keep this short and sweet. About 15 months ago I was hospitalized with acute pancreatitis. Was I an alcoholic? I don't know, I wouldn't call myself one, I drank often but never what I would really call out of control, and admittedly did eat like shit. Now, I definitely understand that the pancreatitis was bad, but while I was in the hospital I also developed complications leading to ARDS and ultimately a stint on ECMO and a vent.
Since then I haven't touched a single drop of alcohol. I work out 3-5 times a week, stay active, eat a much, much healthier and more conscious diet, and really am enjoying life since then. I am scared shitless of having another acute bout of pancreatitis, and even more fearful of developing chronic pancreatitis. If I had to go the rest of my life without drinking (currently 28), I could, BUT, at the same time, I do miss drinking. I mean, just plain and simple I am wondering if it would ever be possible for me, say in 5 years time, to try and have a few beers. I've also had follow up appointments since getting out, liver, kidney, heart and lung function are golden basically, I mean I'm honestly probably a healthier person now than I was before. I'm sure that is hard to make any sort of judgement call without a deeper knowledge of my case, but in general, does acute pancreatitis mean no drinking ever again?
Currently my brother is hospitalized for an acute attack. He is 50 and is a heavy smoker and had been alcoholic for at least 20 years. His diet is heavily meat based and little to no veggies. He is easily 50 lbs overweight. Right now he is on a morphine drip, no food or liquids because they come right back up. His last sugar level was 235. My question is “will he become a diabetic after this attack is over? “
Does anyone know any articles that discuss this issue or have any idea how they would approach this? Thank you
Hello, I have a question for any alternative medicine vets out there regarding artemisinin and pancreatitis. I have a 55lb male neutered australian shepherd who is 13. He was otherwise healthy until about a week ago. He is critically ill with what is believed to be acute pancreatitis. Based on ultrasound, he may have GI cancer, and he has fluid in his abdomen (either from the pancreatitis, a potential mass, or something else entirely). The hospital offered to do exploratory surgery, but it sounded like the prognosis would be 50/50 in the best case, it would be hard on him, and he might not make it home for his last day, which is important to us.
I can elaborate more and send medical records but don't want to inundate. At this point, we basically have him in hospice mode, giving him Cerenia, Famatodine, and occasional Buprenorphine injections. He had 24 hours of IV fluids at the hospital and is now doing 500ml of LR sub-q daily. He has no appetite but still wags his tail sometimes, follows us around, and likes to go on walks. We're realistic and know we are down to our last days, but I'm still researching what I can. There is some research out there that shows artemisinin can help. Just wondering if any vets have tried this with any luck, or have any other suggestions.
We're a bit frazzled, so I apologize if I overlooked any obvious questions. I really appreciate your time. We love him a lot and weren't expecting this.
Not sure of link etiquette but here is one artemisinin/pancreatitis article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857302/ they've also used it with dogs with cancer in clinical studies.
Went to the ER yesterday due to abdominal and lower back pain to get checked out for possible alcohol damage, etc. I’m feeling better already, and I have meds to help with detox. I’m going to another appointment tomorrow to verify the initial diagnosis, etc. I’m nervous but optimistic about that.
I highly recommend seeking medical help when needed. I’m debating trying to go to another inpatient rehab. I’ve been to a couple already but but they’re helpful. Medical costs can be expensive but worth it compared to the cost of alcohol stuff.
I’m 43, hoping to fix my life, again.
So to add some context to the title... I'm 25, trans, MtF, been on HRT now for just over a year and a half. Been on Spiro/Estrodial for the duration of HRT so far. No changes had been planned on my Estrogen delivery.
Last night though I had to go to the ER (unrelated medical reasons) and a blood draw was done. When the results came back the doctor told me my Pancreas was mildly inflamed. I don't drink, so he didn't seem all that concerned over it.
But it was something he mentioned right off the bat - so today I started googling what might be causing this. My thoughts have drifted to ome of two things:
A) My mom and her mom both suffered from Pancreatic issues and the latter died from Pancreatic Cancer. So my family does have a history of Pancreatic issues B) There have been some cases of Estrogen-induced Pancreatitis due to HRT
I guess I'm curious if anyone else has had to deal with said problem? I really hope it doesn't get worse, resulting in me stopping HRT. It is kinda concerning and I wanted to reach out to the trans community to see if it's a common thing or what I should do.
Thanks lovelies <3
This summer, I was recently diagnosed with acute pancreatitis after 3-4 days of being symptomatic with positive CT abdomen scan and elevated lipase (over 400). History of stomach issues that went undiagnosed in the past and during that hospitalization, I was diagnosed with moderate Crohn's Disease (CD) after undergoing a colonoscopy. I was discharged home when my pain was under control with diagnosis of "idiopathic pancreatitis".
Fast forward ~3 months: In mid-October, I started to have pain in the same area (left upper abdomen and epigastric) as well as the exact same kind of pain. I went to emerg sooner this time (since I knew what it was) and was admitted again with acute pancreatitis and elevated lipase levels. I was on a steroid for CD but I am not on any meds at the moment since early September and will start a biologic infusion (entvyio) soon.
I should include that both times, my pain was not unbearable. With fasting and IV fluids, I was able to (mostly) keep the pain under control with pain meds only at night and after eating low-fat solid food. No vomiting and no new referral back pains either. I completely abstain from alcohol, keep a low fat diet, and have a very strict diet to keep my CD under control (gluten free, lactose free, low sugar, low fat, minimal caffeine etc). I really try to adhere to a healthy lifestyle. Now the doctors are considering that it might be "autoimmune pancreatitis" and I received a referral to undergo an EUS (endoscopic ultrasound) of the pancreas. My IGg blood tests came back normal, h.pyhlori negative, and negative celiac. I was discharged home without any medications this October (and currently at home post discharge, I am continuing to have pain and wondering if I should go back to emerg). I am also awaiting an MRI of the small intestine and a repeat MRCP (because the first one was inconclusive as per the radiologist report).
I am wondering if there is something that is being missed here and if any farther investigations need to be done/second opinions need to be asked for. I believe that I have a good head on my shoulders and I strongly believe that I am appropriately concerned: 2 hospital stays in 3 months for acute pancreatitis and a new diagnosis of CD is puzzling to me. Previous to this summer, I was completely healthy (minus the unexplained digestive issues prior to the CD diagnosis). However, the GI doctor following my case has a habit of telling me that I am just anxious and... keep reading on reddit ➡
So last weekend I went to the emergency room with a pain in my abdomen. I've beena moderate drinker for about a year 3-5 beers a day. They did a ultrasound and took some bloodwork. Came back said I had acute pancreatitis but said my bloodwork came back fine. THey sent me home that night and within 12 hour my pain was at a very manageable level more just discomfort. I had no insurance and went to the ER for this. But from everythign I read now what happened to me sounds nothing like pancreatitis. Its not been 5 days and I feel absolutely nothing. Does this sound like they might have just called it pancreatitis to give it a name and get me out the door?
I went to the vet with my 5 year old female chihuahua last Monday and I was told she has acute pancreatitis. We started the treatment with metrobactin the very next day (1/3 pill every 12 hour for 10 days, we’re on day 7 now) and everything seemed to be good, she was playing a bit more than she had been the last few weeks and didn’t seem depressed like before - but she suddenly started whining yesterday over the tiniest things? I couldn’t even put her blanket over her without her crying out but sometimes I could give her little kisses and lift her without a problem? I’m desperate for some answers from anyone who has experienced this
PS. she wasn’t crying out like this before we found out she had acute pancreatitis.
Hey all, looking for some feedback if possible.
I have been a chronic drinker for about 4 years, drinking nearly half a 750ml bottle of whiskey on a nightly basis, as well as beer several times throughout the week. About 8 months ago, I began the process of trying to cut back on my alcohol consumption, taking sporadic breaks a few times each week, sometimes going 3-4 days without alcohol before consuming my regular go-to amount again. Shortly after I started this new on-and-off approach, I began to notice a dull pain in my left abdomen under my rib cage after I binge drank. It was very faint and came and went throughout the day. I wasn't able to put a finger on it, initially assuming it was muscular, but knew right away that something was up. When it didn't go away or subside in a week's time, I grew concerned enough to cut out alcohol completely for about 2 weeks. Then, mistakenly assuming that I was fully healed, I went out of town for a wedding and picked up where I left off and got back on the bottle.
It wasn't long after that that the pain returned with a vengeance, this time radiating throughout my left abdomen to my lower back love handle, as well as on the right side of my abdomen. The pain wasn't unbearable, as it's often described here, but it was painful enough for me to have to take 3-4 advils that night in order to be able to go to sleep. I resorted to scouring Google for a self-diagnosis and all signs pointed to pancreatitis. For the next 5 days straight, I pretty much lived off cans of soup and vegetables, until I was able to see my doc, who told me it sounded like a very mild, "sub-acute" form of pancreatitis. He didn't seem all that concerned, stating that people with actual pancreatitis have symptoms like excruciating pain, severe nausea, and the inability to keep food down. My blood work showed normal lipase/amylase levels and he just told me to quit drinking and take it easy.
That was a few months ago, and I am ashamed to admit that I didn't quit alcohol at that point, instead I just switched to beer. The pain hasn't come back to the degree that it had when I first went to the doctor, but it gets amplified if I were to drink liquor. I've now quit drinking entirely, approaching 12 days sober, and I feel better, but the dullness is still very faintly present. My concern is that I think I may have drank myself to the point of chronic pancreatitis, even though I never had extreme symptoms in my acute episode. Does anyone... keep reading on reddit ➡